نتایج جستجو برای: gp91
تعداد نتایج: 611 فیلتر نتایج به سال:
Acute lung injury represents a wide spectrum of pathologic processes, the most severe end of the spectrum being the acute respiratory distress syndrome. Reactive oxygen intermediates have been implicated as important in the pathobiochemistry of acute lung injury. The endogenous sources that contribute to the generation of reactive oxygen intermediates in acute lung injury are poorly defined but...
Angiotensin II infusion causes endothelial dysfunction by increasing NAD(P)H oxidase-mediated vascular superoxide production. However, it remains to be elucidated how in vivo angiotensin II treatment may alter the expression of the gp91(phox) isoforms and the endothelial nitric oxide synthase (NOS III) and subsequent signaling events and whether, in addition to the NAD(P)H oxidase, NOS III cont...
Nox3, a member of the superoxide-producing NADPH oxidase (Nox) family, participates in otoconia formation in mouse inner ears, which is required for perception of balance and gravity. The activity of other Nox enzymes such as gp91(phox)/Nox2 and Nox1 is known to absolutely require both an organizer protein (p47(phox) or Noxo1) andanactivatorprotein (p67(phox) or Noxa1); for the p47(phox)-depend...
The rapid response to hypoxia in the pulmonary artery (PA), carotid body, and ductus arteriosus is partially mediated by O2-responsive K+ channels. K+ channels in PA smooth muscle cells (SMCs) are inhibited by hypoxia, causing membrane depolarization, increased cytosolic calcium, and hypoxic pulmonary vasoconstriction. We hypothesize that the K+ channels are not themselves "O2 sensors" but rath...
10.1128/IAI.73.8.4539-4547.2005. 2005, 73(8):4539. DOI: Infect. Immun. and Paul Barrow Neil Foster, Scott Hulme, Margaret Lovell, Katharine Reed without Inducing Intestinal Pathology with Serovar Typhimurium Strain F98 Gnotobiotic Piglets from Lethal Challenge Serovar Infantis Strain Protects enterica Salmonella Neutrophils by an Avirulent and Reactive Oxygen Species in Stimulation of gp91 Phag...
Angiotensin II infusion causes endothelial dysfunction by increasing NAD(P)H oxidase–mediated vascular superoxide production. However, it remains to be elucidated how in vivo angiotensin II treatment may alter the expression of the gp91 isoforms and the endothelial nitric oxide synthase (NOS III) and subsequent signaling events and whether, in addition to the NAD(P)H oxidase, NOS III contribute...
During the “respiratory burst” in phagocytes, NADPH oxidase helps kill microbes by producing superoxide anion, O 2 . As illustrated in the cartoon in Fig. 1, the NADPH oxidase complex has several components. In unstimulated cells, four components (p67 phox , p40 phox , p47 phox , and a G protein, Rac) are located in the cytosol, and gp91 phox and p22 phox are membrane bound. Upon stimulation by...
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