Aim : to examine an efficacy of various stimulation methods in a group successful pregnancies. Materials and Methods . In single center retrospective study 47 pregnancy cases were examined after performing embryo transfers at our institution from the years 2017 2021. Patients divided into four groups: i) clomiphene hyperstimulation (CH), ii) with gonadotropin-releasing hormone (GnRH) agonist, i...

BACKGROUND Gonadotropin-releasing hormone (GnRH) analogues are used routinely to prevent a premature luteinizing hormone (LH) surge in women undergoing assisted reproductive technology (ART) treatments. In contrast to GnRH agonists, antagonists produce rapid and reversible suppression of LH with no initial flare effect. OBJECTIVE To review the role of cetrorelix, the first GnRH antagonist app...

Gonadotropin-releasing hormone (GnRH) regulates gonadotropin secretion. We previously demonstrated that the expression of annexin A5 (ANXA5) is stimulated by GnRH in gonadotropes and has a significant role in gonadotropin secretion. It is therefore of interest to know whether other members of the ANXA family, which consists of twelve structurally related members, are also regulated by GnRH. The...