There is no ideal treatment for benign multinodular goitre. Besides surgery, which is recommended for large goitres or when malignancy cannot be excluded, the non-surgical treatment options are levothyroxine therapy and radioiodine ((131)I) therapy. Conventional (131)I therapy [without recombinant human thyroid-stimulating hormone (rhTSH)] has been used for more than a decade in symptomatic non...

The use of thyroid preparations to reduce the size of non-toxic goitres is well established, as is their use in differentiating between high 1311 uptake rates due to thyrotoxicosis and those occurring in non-toxic goitres (Greer and Smith, 1954; Werner and Spooner, 1955). It would seem reasonable to expect that the amount by which the thyroidal 1311 uptake can be suppressed by thyroid preparati...

OBJECTIVE The main objective was to assess iodine status (thyroid volume (Tvol) and urinary iodine concentration (UIC)) and their determinants in Saharawi refugee women. DESIGN A cross-sectional survey was performed during January-February 2007. Tvol was measured by ultrasound and iodine concentration was analysed in spot urine samples and in household drinking water. Anthropometry and Hb con...

BACKGROUND Thyroid malignancies are a heterogeneous group oftumours which show considerable variability in biological behaviour, histological appearances and response to therapy. Thyroid cancer is uncommon and represents only 1% of all malignancies. Objective was to determine the prevalence of malignancy in patients presenting with goitre. This prospective, observational study was conducted at ...

The prevalence of mitral valve prolapse was investigated in 126 patients with hyperthyroidism due to Graves' disease or toxic nodular goitre and that of hyperthyroidism in 64 patients with mitral valve prolapse. One hundred and eleven asymptomatic healthy subjects comprised a control group. The patients with hyperthyroidism were divided into those with Graves' disease and those with toxic nodul...

The aim of this study was to evaluate the significance of measuring calcitonin (CT) plasma concentrations in patients with simple and hyperthyroid goitre treated surgically. Eighty four patients who underwent operations during the years 2000-2002 were analysed. Plasma concentrations of CT were determined by commercially available radioimmunoassay on the day of hospitalisation. Elevated concentr...