Besides two known glycosides, a new furostanol glycoside was isolated from the Fruits of Tribulus terrestris L. The structure of the new furostanol glycoside was established as 26-O-beta-D-glucopyranosyl-(25S)-5alpha-furostane-20(22)-en-12-one-3beta, 26-diol-3-O-alpha-L-rhamnopyranosyl-(1-->2)-[beta-D-glucopyranosyl-(1-->4)]-beta-D-galactopyranoside (1) on the basis of 1D and 2D-NMR techniques,...

in this study we produced and purified a high titer of specific and high affin¬ity fab fragments of anti-digoxin antibody. immunization of rabbits with a conju¬gate of the cardiac glycoside digoxin, coupled by a periodate oxidation method to the amino group of lysine in bovine serum albumin resulted in the production of this type of high titer digoxin-specific antibodies with exceptionally high...

Krimpsiekte (the syndrome associated with chronic cardiac glycoside poisoning) was purportedly induced by Ornithlogalum toxicarium in the Karas mountains area of Keetmanshoop, Namibia. This chinkerinchee species was previously linked to a condition known as 'kwylbek' krimpsiekte in small stock in the Beaufort West district of the Western Cape Province, South Africa. In a dosing trial, respirato...

Certain glycolipid Ags for Valpha14i NKT cells can direct the overall cytokine balance of the immune response. Th2-biasing OCH has a lower TCR avidity than the most potent agonist known, alpha-galactosylceramide. Although the CD1d-exposed portions of OCH and alpha-galactosylceramide are identical, structural analysis indicates that there are subtle CD1d conformational differences due to differe...

Abstract This paper presents a simple and rapid approach to the quantification of various glycosides using high-performance thin-layer chromatography (HPTLC). Different classes glycosides, represented by genistin ononin (both monosaccharidic O-glycosides), rutin (a disaccharidic O-glycoside) luteolin-6-C-glucoside C-glycoside), were successfully separated mixture ethyl acetate‒methanol‒glacial ...

Many disaccharides are usefu1 as lowcariogenic sweet rnaterials or potent bifidus factors, The syntheses of such oligosaccharides have been studied extensively using enzymatic transglycosylation reactions.i "'3) On the other hand, the condensation activity of glycosidases has not been used on a practical level for the synthesis of disaccharides, because the equilibrium of monoand disaccharides ...

A general strategy for the synthesis of analogues of radicamine B has been carried out from D-mannitol. This method has been further extended to the synthesis of analogues of codonopsine and codonopsinine using appropriate Grignard reagents. The hence obtained molecules have been tested against various commercially available glycosidases and found to act as moderate to good inhibitors.

Background: Hesperidin is a bioflavonoid glycoside mainly found in citrus fruit and has been shown radio-protective potential in various measurement systems. Objective: In this article aims to investigate the radio-protective effect of hesperidin on the liver of Sprague Dawely rats. Material and Methods: In this clinical study, 40 male rats were selected randomly and divided into 8 ...

Glycoside phosphorylases hold great potential as catalysts for the synthesis of valuable sugars, glycosides, and glycans or development energy-efficient microbial cell factories. However, number available phosphorylase specificities is rather limited. Here, we show that it possible to establish significant activity in GH3 glycoside hydrolases from Pseudomonas aeruginosa Bacillus subtilis. Singl...