Although it is extremely diff icult to analyze glycans, fortunately, glycan research has been active in Japan, and many analysis technologies and glycosidase essential for glycomic research were created in Japan. 1) On the other hand, at the beginning of the 21st century, it was thought that structural glycomics would be done well by “mass spectrometry.” While mass spectrometry is highly effect...

Glycomics is an emerging discipline, which still lags behind proteomics in terms of the development of bioinformatic tools that are required to track and process vast amounts of raw data, make it accessible to scientists with diverse backgrounds, and deduce important but non-obvious data relationships that can be interpreted in the context of developmental and pathological states of human cells...

This chapter would like to provide a short survey of the most promising concepts applied recently in analysis of glycoproteins based on lectins. The first part describes the most exciting analytical approaches used in the field of glycoprofiling based on integration of nanoparticles, nanowires, nanotubes, or nanochannels or using novel transducing platforms allowing to detect very low levels of...