نتایج جستجو برای: glyceryl trinitrate ointment

تعداد نتایج: 6964  

Journal: :British Journal of Clinical Pharmacology 1982

Journal: :Revista Española de Enfermedades Digestivas 2004

2017
M. Hughes T. Moore J. Manning J. Wilkinson G. Dinsdale C. Roberts A. Murray A.L. Herrick

OBJECTIVES In patients with systemic sclerosis (SSc), fingertip digital ulcers (DUs) are believed to be ischaemic, and extensor surface DUs a result of mechanical factors/microtrauma. Our aim was to assess blood flow response to topical glyceryl trinitrate (GTN) compared to placebo in SSc DUs, looking for differences in pathophysiology between fingertip and extensor lesions. METHOD This was a...

مریم مدرس, , پروین رهنما, ,

Background: Patch forms of glyceryl trinitrate (GTN), also known as nitroglyceril, have proved useful in the management of dysmenorrhea. Increased intrauterine pressure due to exaggerated myometrial contractions is an important factor in the pathogenesis of dysmenorrhea. In a recent study, it was found that GTN caused a significant reduction in the contraction frequency of human myometrial stri...

Journal: :Gut 1999
E A Carapeti M A Kamm P J McDonald S J Chadwick D Melville R K Phillips

BACKGROUND Topical application of glyceryl trinitrate (GTN) ointment heals chronic anal fissures, providing an alternative to the traditional first line treatment of surgical sphincterotomy. AIMS To determine the most effective dose of topical GTN for treatment of chronic anal fissures and to assess long term results. METHODS Seventy consecutive patients with chronic anal fissure, were rand...

Journal: :Chemical & pharmaceutical bulletin 1972
T Nagao S Nishio H Kato K Takagi

Coronary vasodilating activity of chromone derivatives has been reported.2) It is worth examining if chromanone derivatives have a coronary vasodilating effect, since they are chemically related to chromone. In the present study the effects of some benzylidene chromanones and its related compounds on coronary blood flow and myocardial oxygen consumption in anesthetized dogs and also on the oxyg...

Journal: :Postgraduate medical journal 1989
J Navarro Estrada H Saglietti M Dimarco H Casabé R Oliveri

Amlodipine significantly reduced both weekly anginal attack rate and consumption of glyceryl trinitrate tablets in patients with severe coronary artery disease. Exercise tolerance also significantly improved, with a 79% increase in the exercise time to onset of angina and a 59% decrease in ST-segment depression. Blood pressure was decreased, with no significant change in heart rate. No serious ...

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