نتایج جستجو برای: glutamic acid decarboxylase

تعداد نتایج: 753728  

Journal: :Proceedings of the National Academy of Sciences 2000

فیروزرای, محسن, قرانلر, جمیله, نخجوانی, منوچهر, کیهانی, مهین‌دخت ,

Glutamic Acid Decarboxylase(GAD) catalyses the conversion of glutamic acid to Gama amino Butyric Acid(GABA) which is one of the major inhibitory neurotransmitters in central nervous system. GAD has two isoforms with molecular weights of 65 Kda(GAD 65) and 67 Kda (GAD 67). GAD 65 gene is located on chromosome 10 and expressed in β-cells of pancrease. The presence of high concentrations o...

2007
Jongwon Choi Yeong-Min Yoo

− Treatment of mice with Korean Red Ginseng (KRG) changed glutamic acid and GABA content in the mouse brain tissue with pentylenetetrazole (PTZ)-induced convulsion. KRG were orally administered at a dose of 50, 100 mg/kg for two weeks. The electroconvulsions (MES) and PTZ-induced convulsion were reduced but those induced by strychnine, bicuculine and picrotoxin were not. PTZ-induced convulsion ...

Journal: :Annals of the New York Academy of Sciences 2005
Caroline Tilikete Alain Vighetto Paul Trouillas Jérome Honnorat

Glutamic acid decarboxylase (GAD) catalyzes the conversion of glutamic acid to gamma-aminobutyric acid (GABA). Autoantibodies directed against GAD (antiGAD-Ab) have been described in patients with insulin-dependent diabetes mellitus, stiff-man syndrome, and in a few patients with progressive cerebellar ataxia. The presence of these autoantibodies suggests an autoimmune pathophysiological mechan...

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