Introduction: Sleep deprivation can cause hyperalgesia and interfere with analgesic treatments. The aim of the present study was to establish an obligatory sleep-abstinence model and also evaluate the effects of intracerebroventricular (ICV) injection of crocin on pain perception in Wistar rats. Methods: In this experimental study, 35 adult male Wistar rats were randomly divided into 5 groups ...

sleep deprivation (sd) is known to result in a range of neurological, cognitive and physical consequences in chronically-afflicted subjects. the respiratory nuclei of brain-stem tend to play a pivotal part in the regulating sleep function, hence hypothesized to be affected in various types of sleep-related dysfunctions. the purpose of this methodological report is to explain the techniques of r...

the protective effect of a l-type calcium channel blocker, nimodipine, on cell injury induced by oxygen-glucose deprivation (ogd) in pc12 cells was investigated. pc12 cells were exposed to in-vitro oxygen-glucose deprivation (30 minutes and 60 minutes respectively) in the presence or absence of nimodipine (10mm/l) in three different time schedules (pre-24h, pre-3h and concurrently). cellular vi...

The aim of this study was to investigate the effects of sleep deprivation induced anxiety on anaerobic performance. Thirteen volunteer male physical education students completed the Turkish version of State Anxiety Inventory and performed Wingate anaerobic test for three times: (1) following a full-night of habitual sleep (baseline measurements), (2) following 30 hours of sleep deprivation, and...

Study Objective: To examine whether differences in patterns of brain activation under baseline conditions relate to the differences in sleepdeprivation vulnerability. Design: Using blood oxygenation level dependent (BOLD) functional magnetic resonance imaging, we scanned 33 healthy young men while they performed the Sternberg working memory task following a normal night of sleep and again follo...