BACKGROUND AND PURPOSE Subjective determination of the posterior sclera flattening and optic nerve protrusion in MRI is challenging because of the 3D nature of the globe morphology. This study aims to develop and compare quantitative measures of globe flattening and optic nerve protrusion with subjective rating, and assess relationships with papilledema grade and intraocular and CSF pressures. ...

PURPOSE Several properties of ocular tissue make fixation for light microscopy problematic. Because the eye is spherical, immersion fixation necessarily results in a temporal gradient of fixation, with surfaces fixing more rapidly and thoroughly than interior structures. The problem is compounded by the fact that the layers of the eye wall are compositionally quite different, resulting in diffe...

Eye globe abnormalities can be readily detected on dedicated and non-dedicated CT and MR studies. A primary understanding of the globe anatomy is key to characterising both traumatic and non-traumatic globe abnormalities. The globe consists of three primary layers: the sclera (outer), uvea (middle), and retina (inner layer). The various pathological processes involving these layers are highligh...

Colobomatous cyst of the orbit is a rare malformation associated with microphthalmic globe or asymmetrically large globe. Usually, it appears since birth without any sex predilection and can affect one globe or rarely both the globes. A coloboma is a gap or defect in the globe resulting from the failure of the choroidal fissure to close. A coloboma may be an isolated finding or a part of a comp...

This paper presents Living Globe, an application for visualization of demographic data supporting the temporal comparison of data from several countries represented on a 3D globe. Living Globe allows the visual exploration of the following demographic data: total population, population density and growth, crude birth and death rates, life expectancy, net migration and population percentage of d...