نتایج جستجو برای: gliclazide
تعداد نتایج: 499 فیلتر نتایج به سال:
Accurate, sensitive, and simple spectrophotometric and spectrofluorimetric methods were developed for the determination of gliclazide in pharmaceutical formulations and biological fluids. Both methods are based on a coupling reaction between gliclazide and 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole in borate buffer, pH 7.8, in which a yellow reaction product that can be measured spectrophotometric...
A sensitive and selective liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the determination of rosuvastatin in human plasma using gliclazide as an internal standard (IS). Rosuvastatin and gliclazide in plasma were extracted with ethyl acetate, separated on a C18 reversed phase column, eluted with mobile phase of acetonitri...
This study investigates the influence of the solid-state properties melting point (T(m)), enthalpy of melting (DeltaH(m)) and entropy of melting (DeltaS(m)) of a drug on its intrinsic solubility (S(0)). For this purpose, 26 chemically and structurally diverse drugs covering the oral drug space were selected and the S(0), T(m), DeltaH(m) and DeltaS(m) were determined experimentally. The influenc...
1. Anhui Biomedical Institute, Anhui Medical University, Hefei, China 2. Division of Endocrinology, the Second Hospital, Harbin Medical University, Harbin, China 3. Division of Endocrinology, the First Hospital, Harbin Medical University, Harbin, China 4. Tianjin Medical University Metabolic Hospital, Tianjin, China 5. Division of Endocrinology, Tongren Hospital, Capital Medical University, Bei...
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