Journal:
:iranian journal of basic medical sciences
0
abdolreza babaee department of anatomical sciences, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
seyed hassan eftekhar-vaghefi department of anatomical sciences, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
majid asadi-shekaari neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, iran
nader shahrokhi department of physiology, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
samereh dehghani soltani department of anatomical sciences, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
reza malekpour-afshar department of pathology, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
objective(s):melatonin is known as an anti-inflammatory agent, and it has been proven to exert neuroprotection through inhibition of cell death (apoptosis) in several models of brain injury.secondary injury following the primary traumatic brain injury (tbi) results in glial cells activation, especially astrocytes. in fact, astrocyte activation causes the production of pro-inflammatory cytokines...