نتایج جستجو برای: glanzmann

تعداد نتایج: 297  

2015
Mathias Orban Alexander Goedel Jessica Haas Kirstin Sandrock-Lang Florian Gärtner Christian Billy Jung Barbara Zieger Elvira Parrotta Karin Kurnik Daniel Sinnecker Gerhard Wanner Karl-Ludwig Laugwitz Steffen Massberg Alessandra Moretti

Human induced pluripotent stem cells (hiPSCs) represent a versatile tool to model genetic diseases and are a potential source for cell transfusion therapies. However, it remains elusive to which extent patient-specific hiPSC-derived cells functionally resemble their native counterparts. Here, we generated a hiPSC model of the primary platelet disease Glanzmann thrombasthenia (GT), characterized...

2017
C. von Heymann C. Spies H. Grubitzsch H. Schönfeld M. Sander Th. Volk Wolfgang F. Konertz

Zusammenfassung Herzchirurgische Operationen sind mit dem Risiko verbunden, einen relevanten Blutverlust zu erleiden und eine Transfusion von Blutprodukten zu erhalten. Neben dem Blutverlust treten internationalen Studien zufolge schwere Blutungen, die eine Reoperation zur Blutstillung erfordern, bei 3-5% der Patienten auf. Die Morbidität und Mortalität ist signifikant erhöht, so dass eine effe...

Journal: :journal of dentistry, tehran university of medical sciences 0
indu varkey post graduate student, a. b shetty memorial institute of dental sciences, mangalore, india. kavita rai professor, department of pedodontics and preventive dentistry, a.b shetty memorial institute of dental sciences, mangalore, india. amitha m hegde professor, department of of pedodontics and preventive dentistry, a.b shetty memorial institute of dental sciences, mangalore, india. mangalpady shenoy vijaya professor, department of pediatrics, k.s. hegde medical academy, mangalore, india. vinod idicula oommen post graduate student, department of pediatrics, k.s. hegde medical academy, mangalore, india.

glanzmann's thrombasthenia (gt) is a rare, genetically inherited platelet disorder in which the platelet glycoprotein iib/iiia (gp iib/iiia) complex is either deficient or, dysfunctional. the incidence is about 1 in 1,000,000. this case report deals with a 4 year-old girl diagnosed with gt presenting with dental caries and periapical lesions in the primary mandibular first molars. to provide th...

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