INTRODUCTION Many factors can contribute to the development of gingival overgrowth (hyperplasia), including: plaque control; periodontal variables; medications and their relative dose; age; sex; and, genetic factors. Nifedipine is a calcium channel blocker commonly reported to result in drug-induced gingival overgrowth (DIGO). This report outlines a case of gingival overgrowth induced by amlodi...

Angiopoietin-like protein 2 (ANGPTL2) maintains tissue homeostasis by inducing inflammation and angiogenesis. It is produced in infiltrating immune cells or resident cells, such as adipocytes, vascular endothelial cells, and tumor cells. We hypothesized that ANGPTL2 might play an important role as a unique mediator in both systemic and periodontal disease. We demonstrated an increased ANGPTL2 c...

BACKGROUND Goal of this in vivo prospective, randomized, controlled, double-blinded, cross over study was to compare the level of plaque control and gingivitis after use of a novel dental gel (test) vs. A Triclosan/copolymer dentifrice (control). METHODS After coronal polishing, 22 subjects with moderate gingivitis were randomly assigned to brush twice daily with test or control dentifrice fo...

Objective: This case report aims to introduce the black triangle therapy in Miller’s Class IV gingival recession. Methods: The patient complained of spacing between upper and lower teeth causing food accumulation, “long teeth”, receding gums which were unaesthetic during speaking. Clinical examination maxillary mandibular anterior revealed Miller recession, large triangles, no tooth mobility no...

Gingival biotype is described as the thickness of gingiva in faciopalatal or faciolingual dimension. Aesthetic highly con-sidered anterior teeth. A 35-year-old woman came with a complaint that color her front teeth was slightly dark after root canal treatment 10 years ago. Clinical and radiographic examinations upper left lateral incisor showed no signs inflammation infection. Biotype evaluatio...

Periodontal (gum) disease, which is also known as periodontal disease and periodontitis, is a progressive disease which if left untreated may result in tooth loss. Gum disease begins with the inflammation and irritation of the gingival tissues which surround and support the teeth. The cause of this inflammation is the toxins found in plaque, or biofilm, which cause an ongoing bacterial infection.

OBJECTIVE Oral biofilm formation and progression on the surface of the tooth can lead to advanced oral disease such as gingivitis. The purpose of this randomized, controlled, double-blinded study was to evaluate the effects of a novel dental gel on oral plaque biofilm using multimodal imaging techniques. MATERIALS AND METHODS Twenty-five subjects with moderate gingival inflammation (Löe and S...

BACKGROUND Bacteria in dental plaque are one of the main factors causing periodontal disease. The aim was to evaluate and compare the effectiveness of antimicrobial dentifrices with herbal extracts and conventional toothpaste with no antimicrobial action for improvement of oral hygiene and reduction of gingival inflammation. METHODS 48 volunteers with chronic marginal gingivitis were randomly...

OBJECTIVE Pentraxin 3 (PTX3), newly discovered inflammation marker, is a member of acute-phase proteins. The hypothesis, synthesis of gingival tissue and serum PTX-3 increases in the experimental periodontitis model (with 10-day and 40-day periods), was tested by detecting gingival tissue and serum PTX-3 levels in rats with experimental periodontitis. METHODS Thirty rats were randomly divided...

AIM To test whether exacerbated gingival inflammation in pregnancy is associated with increased salivary hormone levels and changes in gingival crevicular fluid (GCF) interleukin-1beta (IL-1beta) and prostaglandin-E2 (PGE2) levels. MATERIAL AND METHODS In this cohort study, 48 pregnant women without periodontitis were evaluated in the first, second, and third trimesters and at 3 months postpa...