Congenital nevocellular or nevomelanocytic nevi (CNN) are considered to be hemartomatous lesions of melanocytes apparent at birth(l-3). Though CNN has an incidence of 1% of all newborns, its spectacular variantthe giant or bathing trunk nevus is extremely rare, occuring once in 5,00,000 live births(l). Giant CNN is of devastating consequence due to the cosmetic disfigurement and the great risk ...

Blue nevus is an uncommon pigmented lesion of dermal melanocytes. By convention, two well defined histologic variants, designated as "common" and "cellular", have been recognized. These lesions have attracted much attention due to its confusion with malignant melanoma. We present a case of a giant congenital cellular blue nevus of neck clinically presenting as malignant melanoma and infiltratin...

BACKGROUND Apoptosis is important for maintenance of tissue homeostasis and often dysregulated in cutaneous neoplasms. The apoptosis inhibitor survivin is expressed in melanoma and non-melanoma skin cancers and benign keratinocytic lesions. Its expression has not been studied in melanocytic nevi. OBJECTIVE We determined the expression pattern of survivin in benign melanocytic nevi in comparis...

Closure of large skin wounds (i.e., burns, congenital giant nevus, reconstruction of traumatic injury) with split-thickness skin grafts requires extensive harvesting of autologous skin. Composite grafts consisting of collagen-glycosaminoglycan (GAG) substrates populated with cultured dermal fibroblasts and epidermal keratinocytes were tested in a pilot study on full-thickness burn wounds of thr...

Congenital melanocytic nevi (CMN) are defined as melanocytic nevi that present at birth or within the first few months of life. Small or medium-sized nevi occur in approximately 1% to 6% of all newborns, whereas giant nevi occur in approximately 1 in 20,000 [1-3]. There are two main considerations in the treatment of CMN. The first is predicting the risk of its transformation to melanoma, and t...

Melanocytic skin tumors are caused by nevus cells, epidermal melanocytes and dermal melanocytes. The aim of the study was to detect the positivity of Demodex spp. in biopsy specimens of skin diagnosed as nevus. In this retrospective study, the specimens obtained from 110 patients diagnosed with nevus and stained by hematoxylin & eosin (H&E) method were assessed for Demodex. Statistical analysis...

To the Editor: Nevus sebaceous (NS) is an epidermal nevus that is comprised predominantly of sebaceous glands in approximately 0.3% of newborns.[1] Clinically, it presents as a single or, less commonly, multiple yellowish‐colored plaques with overlying alopecia, usually confined on the scalp; however, it can also appear on the face, preauricular area, and neck region.[2,3] Here, we reported a c...