DNA damage induced by ultraviolet (UV) radiation can be removed by nucleotide excision repair through two sub-pathways, one general (GGR) and the other specific for transcribed DNA (TCR), and the processing of unrepaired lesions trigger signals that may lead to cell death. These signals involve the tumor suppressor p53 protein, a central regulator of cell responses to DNA damage, and the E3 ubi...

This paper presents a novel technique to derive asymptotic expressions for rare event probabilities for random walks in the quarter plane. For concreteness, we study a tandem queue with Poisson arrivals, exponential service times and coupled processors. The service rate for one queue is only a fraction of the global service rate when the other queue is non empty; when one queue is empty, the ot...

We analyse Nash equilibrium in time of use of a congested facility. Users are risk averse with general concave utility. Queues are subject to varying degrees of random sorting, ranging from strict queue priority to a completely random queue. We define the key "no residual queue" property, which holds when there is no queue at the time the last user arrives at the queue, and prove that this prop...

abstract: the main objective of this paper is to investigate the leadership style between public and private bank and its impact on the job satisfaction in iran. for this purpose, the relationship between transformation and transactional leadership and job satisfaction and the effect of managers’ decision-making strategy and employee’s job perception on it have been considered empirically. the ...

production planning is performed through diverse methods according to the type of the system it is structured upon. one of the most important steps before production planning is to determine which system best fits the firm, and how the facilities should be designed. both job-shop and group-technology systems have their own cons and pros, each of which is suitable to a specific kind of factory. ...

A finite-buffered banyan network analysis technique designed to model networks at high traffic loads is presented. The technique specially models two states of the network queues: queue empty and queue congested (roughly, zero or one slots free). A congested queue tends to stay congested because packets bound for the queue accumulate in the previous stage. The expected duration of this state is...

The problem considered is that of estimating the tail stationary probability for two exponential server queues in series fed by renewal arrivals. We compute the tail of the marginal queue length distribution at the second queue. The marginal at the first queue is known by the classical result for the GI/M/1 queue. The approach involves deriving necessary and sufficient conditions on the paths o...

We consider a discrete-time single-server queue with arrivals governed by a stationary Markov chain, where no arrivals are assumed to occur only when the Markov chain is in a particular state. This assumption implies that off-periods in the arrival process are i.i.d. and geometrically distributed. For this queue, we establish the exact relationship between queue length distributions in a finite...

We consider a discrete-time single-server queue with arrivals governed by a stationary Markov chain, where no arrivals are assumed to occur only when the Markov chain is in a particular state. This assumption implies that o -periods in the arrival process are i.i.d. and geometrically distributed. For this queue, we establish the exact relationship between queue length distributions in a nite-bu...

Abstract: The purpose of this research is to develop algorithm calculating the traffic queue length which is main variable for effective operation at signalized intersection. For the methods to calculate the traffic queue length, there are queue theory and shock wave theory. And, the estimation of traffic queue length by existing point detection system utilizes traffic queue theory calculating ...