BACKGROUND The use of CCR5 antagonists involves determination of HIV-1 tropism prior to initiation of treatment. HIV-1 tropism can be assessed either by phenotypic or genotypic methods. Genotypic methods are extensively used for tropism prediction. However, their validation in predicting tropism of viral isolates belonging to group M non-B subtypes remains challenging. In Cameroon, the genetic ...

in the present study, random amplified polymorphic dna (rapd) and inter-simple sequence repeat (issr) markers were used to estimate genetic diversity and relationships among 35 cluster bean [cyamopsis tetragonoloba (l.) taub] genotypes. for rapd analysis, 20 random primers were used which amplified 164 bands, 147 of which were polymorphic with an average polymorphism of 90.3%. the amplified pro...

in order to investigate production potential, variation and genetic similarity of selected iranian smooth brome grass (bromus intermis) genotypes, an experiment was conducted using clonally propagated materials. genotypes were evaluated for agronomic, phenological and morphological characteristics under a randomized complete block design during 2005 and 2006. results showed that there were sign...

Multi-environment trials (METs) of crop genotypes are costly and require efficient test sites for cost effectiveness. This study aimed to identify efficient test sites for METs of sugarcane (Saccharum spp.) genotypes in Thailand, utilizing data from 10 sugarcane genotypes conducted at nine locations covering different sugarcane growing regions of the country for two crop-classes. Cluster an...

BACKGROUND The aims of this study were to compare various genotypic scoring systems commonly used to predict virological outcome to etravirine, and examine their concordance with etravirine phenotypic susceptibility. METHODS Six etravirine genotypic scoring systems were assessed: Tibotec 2010 (based on 20 mutations; TBT 20), Monogram, Stanford HIVdb, ANRS, Rega (based on 37, 30, 27 and 49 mut...

The increased translocation of plant species for biodiversity restoration and habitat creation has provoked a debate on provenance and genotypic diversity of the used plant material. Nonlocal provenances are often not adapted to the local environmental conditions, and low population genotypic diversity may result in genetic bottlenecks hampering successful establishment. We tested provenance di...

Biodiversity loss is proceeding at an unprecedented rate, yet we lack a thorough understanding of the consequences of losing diversity at different scales. While species diversity is known to impact community and ecosystem processes, genotypic diversity is assumed to have relatively smaller effects. Nonetheless, a few recent studies suggest that genotypic diversity may have quantitatively simil...

Two large experiments designed to detect allozyme-associated heterosis for growth rate in Drosophila melanogaster were performed. Heterosis associated with allozyme genotypes may be explained either by functional overdominance at the allozyme loci, or closely linked loci; or by genotypic correlations between allozyme loci and loci at which deleterious recessive alleles segregate. Such genotypic...

the purpose of this study was to describe the association between grain yield and its components. the experiment was conducted in a randomized complete block design with three replicatsions. results of analysis showed that similar trends were observed for genotypic and phenotypic correlations and in most cases, the value for genetic correlation was greater than phenotypic value. 100-seed weight...