background and aims: crimean-congo hemorrhagic fever (cchf) is a fatal viral disease that occurs in approximately 30 countries. it has the most extensive geographic range among the tick-borne viruses that affect human health. cchf viruses have a tripartite rna genome consisting of large (l), medium (m) and small (s) segments. this study was undertaken to determine the genetic relationship of cc...

conclusions in this study, high prevalence of 91.7% hcmv gb1 genotype was predominant among hcmv-positive uc patients, which suggests that there might be an association between hcmv gb genotype 1 and uc disease. results among 98 patients with uc, only 12 (12.2%) patients were positive for hcmv genome, while the hcmv genome was not detected in any of the controls. (p = 0.002). the distribution o...

background : this comprehensive study was conducted on multi-purpose one-humped camel ( camelus dromedarius ) sera and ticks to assess the epidemiological aspects of the crimean-congo hemorrhagic fever virus (cchfv) in northeast iran. methods : from may 2012 to january 2013, eleven cities were randomly selected in the khorasan provinces of iran as “clusters,” and at least 14 one-humped camels w...

the nutrients are able to interact with molecular mechanisms and modulate the physiological functions in the body. the nutri­tional genomics focuses on the interaction between bioactive food components and the genome, which includes nutrigenet­ics and nutrigenomics. the influence of nutrients on f genes expression is called nutrigenomics, while the heterogene­ous response of gene variants to nu...

flaviviridae are viruses that cause several diseases including dengue fever, japanese encephalitis, murray valley encephalitis, tick-borne encephalitis, west nile encephalitis, yellow fever and hepatitis c virus infection. members of this family have monopartite, linear, single-stranded rna genomes of positive polarity, 9.6-12.3 kb in length. here, we have analyzed the codon usage of 13 species...

Mitochondrial deoxyribonucleic acid (mtDNA) polymorphisms were examinedin bone samples of individuals buried inan early Neolithic (c. 5800–4900 BCE) hunter-gatherer cemetery, Shamanka II, located atthe southwestern tip of Lake Baikal, Siberia. The mainobjective was to compare the mtDNA polymorphisms observed at Shamanka II to those previously reportedfrom the Lokomotiv (early Neolithic) and Ust...

Abstract How ecological divergence causes strong reproductive isolation between populations in close geographic contact remains poorly understood at the genomic level. We here study this question a stickleback fish population pair adapted to contiguous, ecologically different lake and stream habitats. Clinal whole-genome sequence data reveal numerous genome regions (nearly) fixed for alternativ...

We have developed PotatoMASH (Potato Multi-Allele Scanning Haplotags), a novel low-cost, genome-scanning marker platform. designed panel of 339 multi-allelic regions placed at 1 Mb intervals throughout the euchromatic portion genome. These were assayed using multiplex amplicon sequencing approach, which allows for genotyping hundreds plants cost 5 EUR/sample. applied to population over 700 pota...

Genome sequencing is the process of determining in which order nitrogenous bases also known as nucleotides within a DNA molecule are arranged. Every organism’s genome consists unique sequence nucleotides. These provide phenotypes and genotypes cell. In mathematics, Graph theory study mathematical objects graphs made vertices (or nodes) connected by either directed edges or indirect edges. Deter...

The study of the demographic and adaptive history Homo sapiens has entered its golden age with advent genome-wide approaches. analyses genome diversity across different human populations have allowed us to better understand ways in which our species rapidly dispersed around world, how ancestors admixed archaic, now-extinct hominins, effects natural selection on genome. This work has, turn, made...