OBJECTIVE Traditional methods for the analysis of vascular lesion formation are labour intensive to perform - restricting study to 'snapshots' within each vessel. This study was undertaken to determine the suitability of optical projection tomographic (OPT) imaging for the 3-dimensional representation and quantification of intimal lesions in mouse arteries. METHODS AND RESULTS Vascular injury...

Colonoscopy of a 38-year-old woman with persistent diarrhea despite drug therapy revealed no inflammatory changes in the colonic mucosa, but a dark blue, elevated lesion with a diameter of 3 cm was incidentally discovered in the right colonic flexure (Fig. 1A). Computed tomography showed vascular lesions with a clear boundary, 3 cm in diameter, with a patchy contrast effect in the right colonic...

BACKGROUND Very little documentation of spontaneous regression of an angiomatous retinal lesion in v. Hippel-Lindau disease (VHL) exists. It is commonly believed that a spontaneous change of hemangiomas into fibrotic lesions occurred. PATIENTS/METHODS Follow-up examinations of four patients with VHL in the Freiburg VHL study were carried out. RESULTS A 16-year-old girl revealed a vascular l...

BACKGROUND AND PURPOSE New diffusion-weighted imaging (DWI) lesions are common in patients with acute ischemic stroke. They are associated with an initial nonsingle lesion pattern. Previous studies have not analyzed this association in detail. We differentiated nonsingle lesions in 1 vascular supply territory only (scattered lesion pattern) from nonsingle lesions in ≥2 vascular supply territory...

RATIONALE The bone morphogenetic proteins (BMPs), a family of morphogens, have been implicated as mediators of calcification and inflammation in the vascular wall. OBJECTIVE To investigate the effect of altered expression of matrix Gla protein (MGP), an inhibitor of BMP, on vascular disease. METHODS AND RESULTS We used MGP transgenic or MGP-deficient mice bred to apolipoprotein E mice, a mo...

Pendahuluan : Berdasarkan data penelitian tentang kesehatan reproduksi menunjukkan bahwa 75% perempuan di dunia pasti mengalami keputihan,paling tidak sekali dalam hidupnya. Kebersihan organ genitalia yang baik akan menjadi pemicu terjadinya keputihan patologis. Faktanya banyak remaja putri belum mengerti cara merawat genitalia. Tujuan Mengetahui Hubungan Organ Genitalia Dengan Kejadian Keputih...