The globalization of food trade, the growing demand for minimally processed, easy-to-prepare, ready-to-eat food, and proliferation centralized processing pose serious problems safety. Outbreaks infectious diseases alimentary origin stimulate search innovative ways to increase safety shelf life foods. No less important is problem solid waste disposal, a significant share which packaging. Therefo...

alpha-Glycosyl isoquercitrin (AGIQ) is highly absorbable and has been shown to possess antioxidative properties. Based on a favorable safety profile, it has been confirmed as generally recognized as safe (GRAS) compound by the FDA. Nevertheless, safety and toxicity information for AGIQ is still sparse. Therefore, the aim of this study was to test the safety and toxicokinetics of AGIQ in a 90-da...

Carotenoids are known for their antioxidant activity and health promoting effects. One of the richest sources of carotenoids are carrots. However, about 25% of the annual production is regarded as by-products due to strict market policies. The aim of this study was to extract carotenoids from those by-products. Conventional carotenoid extraction methods require the use of organic solvents, whic...

In shrimp/fish aquaculture, feed represents the most expensive production cost. The quantity and quality of diets are primary factors influencing shrimp/fish growth, health status, disease prevention, pound contamination and expenses. Utilization of probiotic bacteria has emerged as a solution with enormous applications in the aquaculture feeding industry. Bacillus species principally B. subtil...

The Thelephora ganbajun mushroom has been found to be a potential rich source of natural antioxidants. In this study, an ultrasound-assisted extraction (UAE) technique together with GRAS (generally recognized as safe) solvents (ethanol and water) was used to maximize the extraction of antioxidants from Thelephora ganbajun. Five extraction parameters (ethanol concentration, solvent to solid rati...

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is particularly troublesome for pediatric patients, as current therapeutic options consist of biologic agents and steroids which alter the immune response and have the harmful side effect of leaving the patient more susceptible to opportunistic infections and eventual surgery. Another option for therapy exists in the form of s...

The percentage of new chemical entities synthesised with low aqueous solubility and high therapeutic efficacy is growing, this presents a major challenge for the drug delivery. To over come this challenge, different methods were developed for the improvement of oral bioavailability, but some have major disadvantages. Recently, oral lipid based formulation is developed for the improvement of ora...

Xylitol is a GRAS ( Generally Recognized as Safe ) polyol commonly used in the food industry and able to promote several benefits health. In addition, it can also be building block molecule for manufacture of different high-value chemicals. Currently, commercial production xylitol occurs by chemical route through catalytic hydrogenation xylose from lignocellulosic biomass. Since this an expensi...

Abstract Background Porcine Parvovirus (PPV) is a Parvovirinae virus that can cause embryonic and fetal loss death mummification in affected pigs. Unlike conventional vaccines, virus-like particles (VLPs) inherit the natural structure of their authentic virions highly immunostimulatory induce strong humoral immune T cell responses with no risk pathogenicity. The production PPV VLPs still challe...