OBJECTIVES To assess the influence of different factors on health-related QOL in adults with epilepsy in Moscow, Russia. METHOD We evaluated quality of life in 242 patients (98 de novo and 144 previously inadequately treated) by using QOLIE-31. Partial cryptogenic or symptomatic epilepsy was diagnosed in 214 patients, in 28-idiopathic generalized epilepsy. Stepwise regression analysis was per...

PURPOSE The ketogenic diet is an alternative treatment for patients with refractory epilepsy. Most studies to date report dietary response in children. There are limited data evaluating the efficacy of the ketogenic diet in adults. This is a report of the long-term outcome in a largely adult population of patients treated with the ketogenic diet for epilepsy. METHOD Twenty-nine adult and adol...

BACKGROUND Sudden unexplained death is a significant cause of mortality in people with epilepsy. Risk factors that have been identified include male sex, poor compliance with medications, and antiepileptic drug (AED) polypharmacy. However, these may not apply to the pediatric population in which the causes of epilepsy differ from the adult population. Therefore, risk factors for sudden unexplai...

UNLABELLED Members of the Brazilian Royal Family carry a rich medical history of epileptic seizures and alike. OBJECTIVE To present the medical knowledge about epilepsy by the time of the Brazilian Empire, as reported by the royal family. METHOD Narrative review of historical facts about D. Pedro I's family health. RESULTS The Royal Family, since D. João VI's generation is full of members...

Frequently, multistable chaos is found in dynamical systems with symmetry. We demonstrate a rare example of bistable chaos in generalized synchronization (GS) in coupled chaotic systems without symmetry. Bistable chaos in GS refers to two chaotic attractors in the response system which both synchronize with the driving dynamics in the sense of GS. By choosing appropriate coupling, the coupled s...

Part of understanding a molecule's conformational dynamics is mapping out the dominant metastable, or long lived, states that it occupies. Once identified, the rates for transitioning between these states may then be determined in order to create a complete model of the system's conformational dynamics. Here we describe the use of the MSMBuilder package (now available at http://simtk.org/home/m...

BACKGROUND This study compared children and adolescents with epilepsy with their healthy peers on measures of social competence. METHODS Children and adolescents with epilepsy (70 subjects aged 11-18 years; 47.1% girls) and their healthy peers in control group (95 subjects aged 11-18 years; 50.9% girls) were compared on measures of social competence from the Child Competence Checklist (part o...

BACKGROUND There is little data on the burden or causes of epilepsy in developing countries, particularly in children living in sub-Saharan Africa. METHODS We conducted two surveys to estimate the prevalence, incidence and risk factors of epilepsy in children in a rural district of Kenya. All children born between 1991 and 1995 were screened with a questionnaire in 2001 and 2003, and those wi...

Abstract Epilepsy is a nervous system disease, which caused by abnormal discharge of brain neurons. The clinical manifestations are generalized seizures, clonus, loss consciousness, and shock. An electroencephalogram (EEG) can accurately capture the changes in EEG activities. Therefore, signals used to detect seizures. In this paper, an epilepsy detection model based on time-gated feature netwo...

We obtain the nonexistence of generalized bent functions (GBFs) from (\ZZ/t\ZZ)^n to \ZZ/t\ZZ (called type [n,t]), for a large new class. Specifically, by showing certain quadratic norm form equations have no integral points, we obtain the universal nonexistence of GBFs with type [n, 2p^e] for all sufficiently large p with respect to n and (p-1)/\ord_2(p), and by computational methods with a we...