The conformations of unsolvated Ac-A14KG3A14K + 2H+ (Ac = acetyl, A = alanine, K = lysine, G = glycine) have been examined by ion mobility measurements and molecular dynamics simulations. This peptide was designed as a model helix-turn-helix motif. It was found to adopt three distinct geometries which were assigned to an extended helical conformation which is only stable at low temperatures (<2...

Salt ions are essential for the folding of nucleic acids. We use the tightly bound ion (TBI) model, which can account for the correlations and fluctuations for the ions bound to the nucleic acids, to investigate the electrostatic free-energy landscape for two parallel nucleic acid helices in the solution of added salt. The theory is based on realistic atomic structures of the helices. In monova...

Smart Village Kelurahan Pondok Ranji Kecamatan Ciputat Timur, Kota Tangerang Selatan dalam pelaksanaannya mengalami banyak kendala dan belum berdampak secara komprehensif karena memadainya sarana prasarana pendukung kegiatan-kegiatan terstruktur. Kemudian, kegiatan-kegiatannya lebih diselenggarakan oleh unsur masyarakat dibandingkan dengan pemerintah atau stakeholder lainnya. Penelitian ini ber...