نتایج جستجو برای: gastroretentive drug delivery system

تعداد نتایج: 2851854  

Anil Bhandari Anupama Singh, Manjeet Singh Vikas Saharan

      Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine wh...

2013
Ganesh B. Patil Saurabh S. Singh Ketan P. Ramani Vivekanand K. Chatap Prashant K. Deshmukh

The aim of the proposed research work was to develop a novel dual-compartment capsule (NDCC) with polymeric disc for gastroretentive dosage form, which will ultimately result in better solubility and bioavailability of Ofloxacin. Floating ring caps were formulated by using different natural polymers, separating ring band and swellable polymer located at the bottom of capsule. Formulated ring ca...

Journal: :biomacromolecular journal 2015
behafarid ghalandari adeleh divsalar ali komeili mahbube eslami-moghadam ali akbar saboury

to answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. in the present paper, controlled metal based drug (pd(ii) complex) release manner of β‑lactoglobulin (β-lg) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...

Journal: :Journal of Pharmaceutical Innovation 2023

Abstract Purpose Gastroretentive drug delivery systems (GRDDS) have attracted interest for enhancement of absorption and bioavailability some drugs. Itopride hydrochloride (ITOP) is a used treatment gastroesophageal reflux other gastric motility disorders, but characterized by narrow window short in vivo half-life. Therefore, it expected that its formulation expanding gastroretentive tablets wo...

Journal: :Kagaku To Seibutsu 2004

ژورنال: پوست و زیبایی 2016
ایمان, مریم, رضوی, سیده‌‌حمیده, قاسمی, روح‌الله,

Transdermal drug delivery (TDD) is a non-invasive, topical administration method for therapeutic agents. Transdermal delivery also has advantages including providing release for long periods of time, improving patient compliance, and generally being inexpensive. Despite these advantages, the use of TDD has been limited by innate barrier functions of the skin. Only small (<500 Da), lipophilic mo...

2017
Mohamed A El Nabarawi Mahmoud H Teaima Rehab A Abd El-Monem Nagla A El Nabarawy Dalia A Gaber

To prolong the residence time of dosage forms within the gastrointestinal tract until all drug is released at the desired rate is one of the real challenges for oral controlled-release drug delivery systems. This study was designed to develop a controlled-release floating matrix tablet and floating raft system of Mebeverine HCl (MbH) and evaluate different excipients for their floating behavior...

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