The roots of Dipsacus asper (DA) have been used as a tonic and analgesic agent in traditional Chinese medicine for the treatment of osteoporosis, low back pain, knee pain, and as an anti-inflammatory agent. Few studies have reported pharmacological gastric activities. In this study, we investigated the effects of dipsacussaponin C (DSC) and 70% ethanol and water extracts of DA on gastritis and ...

Free radicals play an important role in stomach ulcer formation. The present investigation validates the anti ulcer activity of hesperidin, isolated from Citrus sinensis (L.) Osbeck, Rutaceae, through the assessment of its antioxidant potential over stomach mucosal tissue by histological examination. Hesperidin was isolated from the dried peel of C. sinensis, and authenticated by TLC, IR and HP...

Daemia extensa is a well-known traditional plant in India. The plant is having laxative, anthelmintic, astringent, Immunosuppressive, potent antioxidant, in-vitro antibacterial and antifungal activity. The aim was to search for anti-ulcer activity of ethanolic extract of Daemia extensa seed. Ethanolic extract of Daemia extensa seed was considered for its potential to protect gastric mucosa agai...

OBJECTIVE Even though there are many drugs for the treatment of gastric ulcers, these drugs sometimes cannot succeed. Since the 1950s, antidepressant drugs have been used for several non-psychiatric indications. Many antidepressant drugs have been shown experimentally to produce antiulcer activity in various ulcer models. Moclobemide is an antidepressant drug which inhibits monoamine oxidase-A ...

glycyrrhiza glabra l. is used in folk medicine for treatment of stomach disorders includingpeptic ulcers. the hydroalcoholic extract of glycyrrhiza glabra l. (hegg) was evaluated forantiulcerogenic activity and acute toxicity profile in mice. various doses of hegg (50-200mg/kg) were administered orally to animals of different groups. omeprazole and cimetidine atdoses of 30 and 100 mg/kg were us...

Channa striatus (Haruan) is Malaysian freshwater fish that is traditionally used to treat ailments related to wound and also ulcers. The aimed of the present study was to determine the mechanisms of anti-ulcer activity of chloroform: methanol extract of C. striatus fillet (CMCS) in rats. The antiulcer profile of CMCS, given orally in the doses of 50, 250 and 500mg/kg, was assessed using the eth...

Memora nodosa is popularly known as "caroba" and widely found in the Cerrado regions of Brazil. In traditional medicine, the leaves and stems are used for the healing of external ulcer and the roots for abdominal pain. This study investigated the effect of ethanolic roots extract of Memora nodosa (EMN) on the gastric mucosa of mice. In the indomethacin induced gastric ulcer model, the treatment...

The high risk of developing gastric ulcers by various non-steroidal anti-inflammatory drugs has affected their common application in the treatment of collagen diseases like arthritis. Indomethacin, a potent anti inflammatory agent, has been found to induce gastric irritation and ulceration (1). In humans, it is expected that pregnancy which may exert physiologic stress would aggravate gastric u...

In this study, the antiulcerogenic effect of essential oil from Baccharis dracunculifolia was evaluated using the model of acute gastric lesions induced by ethanol. The ulcerative lesion index (ULI) was significantly reduced by oral administration of the essential oil of B. dracunculifolia at doses of 50, 250 and 500 mg/kg which reduced the lesions by 42.79, 45.70 and 61.61%, respectively. The ...

Gum arabic is used throughout the world for various purposes including food additive and pharmaceutical excipient. The present study was undertaken to determine the effect of gum arabic on gastric ulcers in rats. The influence of gum arabic on the antiulcer activity of ranitidine, a known antiulcer drug was also evaluated. The antiulcer study was carried out in acetic acid induced chronic gastr...