The human sodium iodide symporter (hNIS) is an intrinsic transmembrane protein that mediates the active transport of iodide across the basolateral membrane of thyroid follicular cells. In addition to normally functioning thyroid tissue, various extrathyroidal tissues, including salivary gland, lacrimal gland, gastric mucosa, choroid plexus, and lactating mammary gland, have been demonstrated to...

Gastro-oesophageal reflux (GOR) and bronchoaspiration of gastric content are risk factors linked with ventilator-associated pneumonia. This study was aimed at evaluating the effect of a nasogastric tube (NGT) incorporating a low-pressure oesophageal balloon on GOR and bronchoaspiration in patients receiving mechanical ventilation. Fourteen patients were studied in a semi-recumbent position for ...

A 27-year-old woman with severe neurological disability and portal hypertension secondary to Wilson’s disease was referred for endoscopic closure of a chronic gastrocutaneous fistula following the removal of a percutaneous endoscopic gastrostomy (PEG) tube 8 months previously (●" Fig.1). The patient suffered from skin denudation caused by leakage of gastric secretions. At upper gastrointestinal...

The fucosylated ABH antigens, which constitute the molecular basis for the ABO blood group system, are also expressed in salivary secretions and gastrointestinal epithelia in individuals of positive secretor status; however, the biological function of the ABO blood group system is unknown. Gastric mucosa biopsies of 41 Rhesus monkeys originating from Southern Asia were analyzed by immunohistoch...

This study investigated the quantitative polyphenolic constituents and gastroprotective effects of aqueous leaf extracts of Spondias mombin and Ficus exasperata against indomethacin-induced gastric ulcer in rats. Ulceration was induced by a single oral administration of indomethacin (30 mg/kg body weight). Wistar rats were pretreated with esomeprazole (reference drug) at a dose of 20 mg/kg body...

This study examined the effects of eradication of Helicobacter pylori (H pylori) infection on gastric mucosal morphology and acid secretion. Sixteen H pylori positive patients with enlarged gastric body folds were divided into two groups: (a) patients with moderate enlargement (fold width: 6 to 10 mm, n = 8) and (b) patients with severe enlargement (> 10 mm, n = 8). After successful treatment, ...

The aim of the present study in the pig was to describe the biliary and pancreatic secretory component of the migrating myoelectric complex (MMC) during the interdigestive period and after feeding, and to examine the effects of the extracorporal diversion of biliary or pancreatic secretions on the MMC and on the cyclical variation of intraduodenal pH. In a first trial six pigs (50.6 +/- 1.6 kg)...

Aim: The convenient cuff pressure of the endotracheal tube, fixes tube in correct position , provides sufficient ventilation, and prevents complications. In this study, we aimed to evaluate adequacy training experience nurses working intensive care units on patients with intubation tracheostomy. Material Methods: Fifty chest diseases hospital agreed participate study. 10-question questionnaire ...