Guaifenesin, a highly water-soluble active (50 mg/mL), classified as a BCS class I drug.Owing to its poor flowability and compressibility, formulating tablets especially high-dose one,may be a challenge. Direct compression may not be feasible. Bilayer tablet technology appliedto Mucinex®, endures challenges to deliver a robust formulation. To overcome challengesinvolved in bilayer-tablet manufa...

Recent studies indicate that PEM fuel cell performance may be strongly influenced by in-plane permeability of the gas diffusion layer (GDL). The urrent study employs a radial flow technique for obtaining in-plane permeability of GDLs, using either gas or liquid as the impregnating fluid. A odel has been developed and experimentally verified to account for compressibility effects when permeabili...

Following the work of Leutheusser [Physica A 127, 667 (1984)], the solution to the Percus-Yevick equation for a seven-dimensional hard-sphere fluid is explicitly found. This allows the derivation of the equation of state for the fluid taking both the virial and the compressibility routes. An analysis of the virial coefficients and the determination of the radius of convergence of the virial ser...

Direct numerical simulations of free round jets at a Reynolds number ($Re_{D}$) $5000$, based on jet diameter ($D$) and jet-exit bulk velocity ($U_{e}$), are performed to study turbulence characteristics supercritical pressures. The consists $\mathrm{N_{2}}$ that is injected into same temperature. To understand turbulent mixing, passive scalar transported with the flow unity Schmidt number. Two...

An analytical equation of state was applied to calculate the thermodynamic properties for argon.The equation of state is that of Song and Mason. It is based on a statistical-mechanical perturbationtheory of the hard convex bodies and can be written as fifth-order polynomial in the density. Thereexist three temperature-dependent parameters: the second virial coefficient, an effective molecularvo...