Six biflavonoids were isolated from G. madruno, one of which, 7''-O-(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu²⁺, was studied by means of a TBARS assay. The antioxidan...

Twelve xanthones were isolated from the hexane extract of the heartwood of Garcinia mangostana from Myanmar. Their structures were determined using 1D and 2D NMR techniques

The methanol extract of the leaves of Garcinia nervosa var. pubescens King, which showed strong inhibitory effects on platelet-activating factor (PAF) receptor binding, was subjected to bioassay-guided isolation to obtain a new biflavonoid, II-3,I-5, II-5,II-7,I-4',II-4'-hexahydroxy-(I-3,II-8)-flavonylflavanonol together with two known flavonoids, 6-methyl-4'-methoxyflavone and acacetin. The st...

OBJECTIVES Over the past years, there has been a growing number of knee osteoarthritis (KOA) patients who are not willing to comply with long-term non-steroidal anti-inflammatory drugs (NSAID) treatment and wish to use herbal anti- rheumatic medicine. This study assessed the clinical effects of Garcinia kola (GK) in KOA patients. PATIENTS AND METHODS Prospective randomized, placebo controlled...

A new compound with a peroxisomicine (dimeric hydroxyanthracenone type) structure was isolated from Karwinskia parvifolia and denominated peroxisomicine A4 (PA4). The stereochemistry of the stereogenic centers of this compound and the previously isolated peroxisomicine A3 (PA3, 3) was elucidated using CD, 13 C NMR and 1 H NMR spectra. Four peroxisomicine stereoisomers were cytotoxic to Chang an...

the aim of the study was to investigate the improving effect of garcinia cambogia extract on performance metrics, and serum non-esterified fatty acids (nefa) and c-reactive protein (crp) levels in rats fed with atherogenic diet. thirty, one-year-old, female sprague-dawley rats were randomly assigned to threeexperimental groups of ten animals each. control group was fed with basal diet (2% liqui...

the aim of the study was to investigate the preventive effects of dietary garcinia cambogia extract onlipid metabolism and serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast)and gamma-glutamyle transferase (ggt) in rats fed high-lipid diet. thirty female, one-year-old sprague-dawley rats were used and separated into three equal groups. group 1 (control group) wa...

background: garcinia kola seed is consumed indiscriminately in nigeria without recourse to its potential toxicity. therefore, this study was aimed at assessing the toxicity of the aqueous extract of g. kola seeds on selected tissues of male rats.  methods: thirty male rats (215.00 ± 18.58 g) were assigned into four groups: a, b, c and d which received 0.5 ml of distilled water, 25, 50 and 100 m...