نتایج جستجو برای: ga mlr

تعداد نتایج: 38478  

Journal: :Brain research 1992
N Kraus T McGee T Littman T Nicol

Ongoing studies are aimed at identifying the neural pathways responsible for the middle latency response (MLR). These studies involve the analysis of surface and intracranial potentials following pharmacologic inactivation (with lidocaine) of discrete regions of the guinea pig brain. Previous investigations have shown that MLR surface waves recorded over the temporal lobe originate from pathway...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Frédéric Brocard Dimitri Ryczko Karine Fénelon Raja Hatem Delphine Gonzales François Auclair Réjean Dubuc

A unilateral activation of the mesencephalic locomotor region (MLR) produces symmetrical bilateral locomotion in all vertebrate species tested to date. How this occurs remains unresolved. This study examined the possibility that the symmetry occurred at the level of the inputs from the MLR to reticulospinal (RS) cells. In lamprey semi-intact preparations, we recorded intracellular responses of ...

Dichloroacetate (DCA) is a simple and small anticancer drug that arouses the activity of the enzyme pyruvate dehydrogenase (PDH) through inhibition of the enzyme pyruvate dehydrogenase kinases (PDK1-4). DCA can selectively promote mitochondria-regulated apoptosis, depolarizing the hyperpolarized inner mitochondrial membrane potential to normal levels, inhibit tumor growth and reduce proliferati...

The IL-1β play a major role in inflammatory disorders and IL-1β production inhibitors can be used in the treatment of inflammatory and related diseases. In this study, quantitative relationships between the structures of 46 pyridazine derivatives (inhibitors of IL-1β production) and their activities were investigated by Multiple Linear Regression (MLR) technique Stepwise Regression Method (ES-S...

Dichloroacetate (DCA) is a simple and small anticancer drug that arouses the activity of the enzyme pyruvate dehydrogenase (PDH) through inhibition of the enzyme pyruvate dehydrogenase kinases (PDK1-4). DCA can selectively promote mitochondria-regulated apoptosis, depolarizing the hyperpolarized inner mitochondrial membrane potential to normal levels, inhibit tumor growth and reduce proliferati...

Journal: :Applied Soft Computing 2022

The establishment of water quality prediction models is vital for aquatic ecosystems analysis. traditional methods index (WQI) analysis are time-consuming and associated with a high degree errors. These days, the application artificial intelligence (AI) based trending capturing nonlinear complex processes. Therefore, present study was conducted to predict WQI in Kinta River, Malaysia by employi...

Journal: :Hearing research 1990
J A Crowther J M Miller P R Kileny

Increased recent interest in the middle latency response (MLR) has necessitated a clarification of the possible effects of anesthesia on the response. Our study was designed to examine the changes, in the guinea pig MLR, which occurred during anesthesia with ketamine, xylazine or both ketamine and xylazine. Under anesthesia the response remained present and the threshold remained stable. After ...

2013

This chapter deals with computation of viscosity of 35 alcohols at 20C with the computational tools Multi-linear Regression (MLR) and Associative Neural Network(ASNN) . The four descriptors are used which are variable Zagreb index, Number of Hydroxyl Groups(NOH), Molecular Weight (MW) and Number of Carbon atoms (Nc). MLR is used to optimize the parameter(λ) in the variable Zagreb index by minim...

2017
Lihui Shi Xiaoqi Qin Huijun Wang Yonghui Xia Yuanyuan Li Xuejing Chen Lei Shang Yu-Tzu Tai Xiaoyan Feng Prakrati Acharya Chirag Acharya Yan Xu Shuhui Deng Mu Hao Dehui Zou Yaozhong Zhao Kun Ru Lugui Qiu Gang An

Elevated inflammatory markers are associated with poor outcomes in various types of cancers; however, their clinical significance in multiple myeloma (MM) have seldom been explored. This study investigated the prognostic relevance of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) in MM. Totally 559 MM patients were included in th...

Journal: :American journal of physiology. Heart and circulatory physiology 2005
Alexandr M Degtyarenko Marc P Kaufman

A central motor command arising from the mesencephalic locomotor region (MLR) is widely believed to be one of the neural mechanisms that reset the baroreceptor reflex upward during exercise. The nucleus tractus solitarius (NTS), a dorsal medullary site that receives input from baroreceptors, may be the site where central command inhibits baroreceptor input during exercise. We, therefore, examin...

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