Background and Purpose: Candidiasis, an important fungal infection, is considered the fourth most common nosocomial blood stream infection. Nowadays, because of increased fungal resistance to antibiotics, the use of herbal medicine has gained particular attention. Cyclamen species are medicinal plants containing triterpenoid saponins, which are shown to have antimicrobial properties. Materi...

Leaf, fruit, stem, bark and root of Zanthoxylum americanum were investigated for antifungal activity with 11 strains of fungi representing diverse opportunistic and systemic pathogens, including Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. All extracts demonstrated a broad spectrum of antifungal activity and inhibited at least eight fungal species in a disk diffusion ass...

Cytotoxic activity screening of ethyl acetate fungal extracts derived from the marine sponge Neopetrosia chaliniformis AR-01Muh. Ade Artasasta, Yanwirasti, Akmal Djamaan, Dian Handayani

Fractions obtained from partitioning of aerial methanolic extract of Euphorbia Aellenii with chloroform (E2), ethyl acetate (E3), n-butanol (E4) and water (E5) were investigated in vitro for their phytotoxicity, insecticidal, anti-leishmanial, cytotoxicity, antibacterial and antifungal activities. Sample E2 appeared to have significant phytotoxic activity. In the insecticidal screening study o...

Bioassay-guided metabolomic analyses led to the characterization of four new 20-membered glycosylated polyketide macrolactams, macrotermycins A-D, from a termite-associated actinomycete, Amycolatopsis sp. M39. M39's sequenced genome revealed the macrotermycin's putative biosynthetic gene cluster. Macrotermycins A and C had antibacterial activity against human-pathogenic Staphylococcus aureus an...

The antagonistic interaction between marine fungi and marine bacteria was investigated using 19 bacterial species isolated from marine biofilm and 46 waterborne fungal isolates obtained from Hong Kong waters. Of the 46 fungal isolates, 70% inhibited the growth of at least 1 target bacterial species. Active fungal strains belonged mainly to the genera Cladosporium, Paraphaeosphaeria, Trichoderma...

Fungal diseases have always been a major problem for tomato crops. Growers generally use chemical fungicides to treat this type of diseases. However, these products are toxic the environment and consumer, especially if pre-harvest interval is not respected. The present study aims find non-polluting alternatives. Five plant extracts ( Peganum harmala, Ocimum basilicum, Caralluma europaea, Nerium...