BACKGROUND Although gastric adenoma is widely accepted as a precursor of gastric cancer, pre-existing adenoma is not always detected in gastric cancer patients. OBJECTIVE To investigate the clinical characteristics of early gastric cancer (EGC) arising from adenoma, compared with those of EGC without pre-existing adenoma. METHODS Patients who underwent endoscopic resection for EGC at a sing...

an ectopically placed parathyroid in the mediastinum is a rare cause of persistent or recurrent primary hyperparathyroidism. they are rarely in a huge size. we report a case of a 70-year-old man with a history of total parathyroidectomy and thymectomy presented with a lack of appetite, nausea, and generalized bone pain, polydipsia and a calcium level of 14.4 mg/dl. 99m tc-sestamibi scintigraphy...

Gonadotropinoma is the most common non-functional pituitary adenoma comprising 10%–30% of all adenomas. They are benign slow-growing tumours originating from adenohypophysis and rarely become malignant. Its presentation can be atypical, such as visual disturbance, patients presenting to an ophthalmologist for correction eventually found have a field defect. Here, we report case 59-year-o...

Metformin and insulin differently affect the risk of colon cancer in type 2 diabetic patients, however their effects on colon adenoma is not clear. PubMed, ISI, Scopus and Cochrane databases were searched for studies reporting. The outcomes were total adenoma; advanced adenoma and recurrent adenoma. Traditional and Bayesian meta-analysis were conducted via random-effects models. Odds ratios (OR...

a rare case of squamous cell carcinoma ex pleomorphic adenoma in maxillary sinus is presented. the patient is a 50-year-old woman presenting with a slow-progressive swelling in left side of her face that she has noticed 2 years earlier. the lesion was not painful and caused asymmetry and mild exophthalmos. microscopic examination revealed that the tumor was composed of two components partly of ...

a 19-year-old girl referred to our clinic complaining of a painless lump on the left side of her tongue.  the patient had no history of dysphagia, lingual paresthesia or bleeding. physical examination revealed the presence of multiple enlarged lymph nodes on the left side of her neck.  histopathology of lingual mass and lymph nodes showed pleomorphic adenoma.  to our knowledge, this is the firs...

Background: Visfatin is an adipocytokine secreted by visceral adipose tissue. It has been shown that adipocytokines may contribute to the induction of carcinogens and progression of tumors. Previously, we found a significant increase in the visfatin serum level in colorectal cancer patients. Herein, we investigated if this cytokine increases in patients with colorectal adenoma as a precursor of...

We report a rare case of pleomorphic adenoma arising from the lateral nasal wall which was incidentally detected at a very early stage. A 38-year-old man presented to the ophthalmology department with a 2-year history of epiphora from the left eye. He was referred to otorhinolaryngology department as a candidate for endoscopic dacryocystorhinostomy. Nasal endoscopy revealed a polypoid mass on t...

Ectopic parathyroid adenomas can be a cause of recurrent and refractory hyperparathyroidism. Majority are located in the neck region, however very few cases they within mediastinum. In such excision via cervical approach is not possible it becomes diagnostic as well surgical challenge. Excision thoracoscopic preferred this regard. Here we represent case ectopic adenoma embedded thymus gland whi...