نتایج جستجو برای: fuhrman grade
تعداد نتایج: 167592 فیلتر نتایج به سال:
BACKGROUND Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer in adults. Our aim is to evaluate genes and miRNAs expression profiles involved with angiogenesis and tumor characteristics in ccRCC. METHODS The expression levels of miRNAs miR-99a, 99b, 100; 199a; 106a; 106b; 29a; 29b; 29c; 126; 200a, 200b and their respective target genes: mTOR, HIF1-α, VHL, PDGF,...
The reporting of renal cell carcinoma is facilitated by the provision of a checklist to ensure that pathologists provide all of the essential information to enable clinicians to optimize patient care. Classification of renal tumors is complicated by the wide range of morphologic types of renal cell carcinoma, some of which have recognized subtypes. Cytogenetic data have clarified the morphologi...
The receptor tyrosine kinase of EphA2 has been shown frequently overexpressed in various types of human carcinomas, which implicated that it plays important roles in carcinogenesis. Although EphA2 protein expression has been investigated in many types of human carcinomas, the relationship between the expression of EphA2 protein in clear cell renal cell carcinoma was not well documented. In the ...
BACKGROUND PD-L1 is a glycoprotein from the family of T-cell co-stimulatory molecules that are constitutively expressed by macrophages. Aberrant expression of PD-L1 is observed in human cancers associated with inhibition of the tumor-directed T-cell immune response. There are few reports in the literature evaluating PD-L1 expression in association to prognosis specifically in renal cell cancer ...
PD-L1 expression in primary clear-cell renal cell carcinoma (ccRCC) increases the likelihood of response to anti-PD-1 inhibition, but fails to identify all responders. We hypothesized that PD-L1 levels assessed in randomly selected areas of the primary tumors may not accurately reflect expression levels in metastatic lesions, which are the target of systemic therapy. Therefore, we compared PD-L...
School improvement policies converge on urban public schools in ways that paradoxically compromise school improvement—a challenge some have called a heightened state of policy incoherence (Fuhrman, 1993). These schools face a barrage of demands from various sources including federal and state governments, local school boards, unions, and community groups—these demands focus on numerous aspects ...
background and objective: evaluation of tumor proliferative activity may provide a predicting parameter to estimate biologic aggression and a subsequent prognosis that has been evaluated in many malignancies. we have selected renal cell carcinoma (rcc) in this study. to determine tumor proliferative activity, ki67 antibody was applied and results were compared with apoptosis, applying p53 antib...
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