Brown adipose tissue (BAT) is related with energy expenditure, in contrary to fat-storing white adipose tissue. Recent studies have shown that cold exposure could be related with the expression of BAT in adult subjects assessed by ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography (PET). In addition, the application in previous clinical trials showed positive effect of xanthigen containi...

The diatom Cyclotella cryptica was grown under low- and high-intensity white light of 50 and 500 micromol photons m-2 s-1, respectively. Western immunoblotting showed that the diatom adapted its light-harvesting apparatus, giving rise to different amounts of distinct fucoxanthin chlorophyll a/c binding polypeptides (Fcp). The amount of Fcp2 was approximately two-fold higher under low-light than...

Despite the growing interest in diatom genomics, detailed time series of gene expression in relation to key cellular processes are still lacking. Here, we investigated the relationships between the cell cycle and chloroplast development in the pennate diatom Seminavis robusta. This diatom possesses two chloroplasts with a well-orchestrated developmental cycle, common to many pennate diatoms. By...

The present study aimed to evaluate the efficiency of microalgae metabolites as a ligand for anti-diabetic target proteins namely Glucokinase, Fructose-1, 6-bisphosphatase, Glycogen synthase kinase, Cytochrome P450, multi-drug resistant protein, and Peroxisome proliferators activated receptor-γ (PPARγ) using computational approach. Three-dimensional structure of microalgal metabolites retrieved...

Carotenoids exert beneficial effects on human health through their excellent antioxidant activity. To increase carotenoid productivity in the marine Pennales Phaeodactylum tricornutum, we genetically engineered the phytoene synthase gene (psy) to improve expression because RNA-sequencing analysis has suggested that the expression level of psy is lower than other enzyme-encoding genes that are i...

In an effort to understand the more general mechanisms and rates of pre-depositional reactions that transform organic matter, the types and relevant time scales of reactions that transform carotenoid pigments in the oceanic water column were studied. In the present study, a model was constructed for organic matter cycling that consisted of three parts: 1) the synthesis of carotenoid pigments by...