BACKGROUND Gibberellin-regulated protein (GRP, also known as peamaclein) was recently identified as a new marker allergen related to systemic reactions in peach allergy; however, its role in other fruit allergies is unknown. OBJECTIVE To investigate the allergenicity of Japanese apricot (JA) GRP and clarify the clinical characteristics of JA allergy patients with GRP sensitization. METHODS ...

Fructus Arctii is used as a traditional herbal medicine to treat inflammatory diseases in oriental countries. This study aimed to investigate effect of F. Arctii extract on intestinal barrier function in human intestinal epithelial Caco-2 cells and to reveal the active component of F. Arctii. We measured transepithelial electrical resistance (TEER) value (as an index of barrier function) and ov...

cow’s  milk  anaphylaxis is  the  most  common  food-induced  anaphylaxis in  iranian children. the clinical and laboratory findings of cow’s milk anaphylaxis are evaluated in this study. all children who had experienced cow’s  milk anaphylaxis and had been referred to immunology, asthma and allergy research center during a 5-year period were considered. after fulfilling a questionnaire, patien...

Lipid transfer proteins (LTP) constitute a family of proteins widely distributed through the plant kingdom [1]. Allergenic LTP have been identified in tree pollen and weeds, plant food allergen sources and latex. The primary sensitizer agent and the fruit mostly involved seems to be the peach [2]. Allergy to LTP has been mainly described in Italy, Spain and Greece [3] and only exceptionally in ...