BACKGROUND Thyroid function test results of healthy pregnant women differ from those of healthy non-pregnant women. This study aimed to determine trimester-specific reference ranges for total tetraiodothyronin (T4), free T4, total triiodothyronin (T3) and thyroid stimulation hormone (TSH) using electrochemiluminescence techniques from apparently healthy pregnant women in Basrah. MATERIAL AND ...

Serum concentrations of T4, T3, rT3, and TSH were measured by radioimmunoassay in 45 patients suffering from beta-thalassaemia. A TRH stimulation test was performed and the binding capacity of TBG and TBPA for T3 and T4 measured by reverse flow zone electrophoresis in a group of these patients. Mean T4 serum concentration was lower in thalassaemic patients than controls; T3, rT3, TSH levels, an...

The postulate that thyroxine (T4) in plasma enters tissues by protein-mediated transport or enhanced dissociation from plasma-binding proteins leads to the conclusion that almost all T4 uptake by tissues in the rat occurs via the pool of albumin-bound T4 (Pardridge, W. M., B. N. Premachandra, and G. Fierer. 1985. Am. J. Physiol. 248:G545-G550). To directly test this postulate, and to test more ...

*Dept. of NM and RIA, LHRC, Mumbai Received: 20.06.2011; Accepted: 10.08.2013 Sir, This is in reference to the Original article “Endocrine Changes in Male H i v Patients” by LP Meena et al in JAPI 2011;59:365-371. The respected authors have estimated only TSH unlike all other previous publications on this subject, cited in reference 3, 10, 11, 12 wherein free T3 and free T4 were measured along ...

BACKGROUND Randomized trials established chemoradiotherapy as standard treatment for advanced laryngeal cancer. Patients with large-volume T4 disease (LVT4) were excluded from these trials. The purpose of this study was to report T4 laryngeal cancer patient outcome, including those with LVT4 disease, treated with chemoradiotherapy. PATIENTS AND METHODS This study is a retrospective subset ana...

2. Meinhold H, Wenzel KW. Comparative methodological studies with six commercial FF4 kits. Nucl Compact 1985;16:317-20. 3. Ross HA. An indirect assay for serum free thyroxin (FF4) using monoclonal antibody coated tubes and radiolabeled thyroxin. Ibid., 1985;32:314-6. 4. Stockigt JR, Stevens V, White EL, Barlow JW. “Unbound analog” radioimmunoassays for free thyroxin measure the albuminbound hor...

Several indices of thyroid function were assessed in 74 patients with chronic renal failure. Sixty patients had undergone haemodialysis for varying periods. Within the first six months of haemodialysis treatment protein-bound iodine and total thyroxine (T4) levels rose, but after this T4 levels and the free thyroxine index fell progressively. Three out of the 12 patients who had undergone haemo...

Sixty six clinically proven hypothyroid subjects were studied using radioimmunoassay techniques for estimation of serum thyroid hormones and pituitary TSH concentrations. The mean level for serum TSH was significantly elevated while the mean levels for serum T4, 13 and Free T4 were significantly low. A significant positive correlation was found between 14 and T3 and between T4 and FTI. Serum TS...

A blunted thyroid-stimulating hormone (TSH) response to exogenous thyrotropin-releasing hormone (TRH) has been reported to occur consistently in patients with major depression and less consistently in patients with Alzheimer's disease (AD). In this study we compared the TSH response to TRH in a large group (n = 40) of AD patients, elderly patients with major depression (n = 17), and age-matched...

We studied 145 clinically euthyroid patients on maintenance methadone therapy for narcotic withdrawal, to characterize abnormalities in thyroid-function tests induced by methadone. About a third had increased total thyroxin (T4) and total triiodothyronine (T3) concentrations in serum. The mean concentrations of T3, T4, and thyroxin-binding globulin (TBG) in serum were significantly greater (P l...