this paper addresses the problem of the fractional sliding mode control (fsmc) for a mems optical switch. the proposed scheme utilizes a fractional sliding surface to describe dynamic behavior of the system in the sliding mode stage. after a comparison with the classical integer-order counterpart, it is seen that the control system with the proposed sliding surface displays better transient per...

(in alphabetic order by speaker surname) Speaker: Michael Chevalier (University of California, San Francisco) Title: An exact CME/SSA formulation for separating timescales in stochastic biological networks Abstract: Noise and stochasticity are fundamental to biology and derive from the very nature of biochemical reactions where thermal motion of molecules translates into randomness in the seque...

We propose React(C ), an expressive programming language for stochastic modeling and simulation in systems biology that is based on biochemical reactions with constraints. We prove that React(C ) can express the stochastic π-calculus, in contrast to previous rule-based programming languages, and further illustrate the high expressiveness of React(C ). We present a stochastic simulator for React...

The number of molecules involved in a cell or subcellular structure is sometimes rather small. In this situation, ordinary macroscopic-level fluctuations can be overwhelmed by non-negligible large fluctuations, which results in drastic changes in chemical-reaction dynamics and statistics compared to those observed under a macroscopic system (i.e., with a large number of molecules). In order to ...

Evidence from published nuclear magnetic resonance studies of enzyme-substrate and enzyme-inhibitor systems systems shows that substrates are confined at the active site of the enzyme, have a relatively long residence time, and tumble in solution as an enzyme-substrate complex. The consequences of this "substrate anchoring" with regard to the catalytic power of enzymes are considered. It appear...

The usefulness of Bayesian statistical methods for the modelling of biochemical reactions is examined. With simulated data, it is shown that these methods can effectively fit mechanistic models of sequences of enzymatic reactions to experimental data. These methods have the advantages of being relatively easy to use and producing probability distributions for the model parameters rather than po...

New crystallographic techniques make it possible to observe directly all of the intermediates in an enzymatic reaction. Such a series of structures can be combined to create a detailed movie of enzymatic catalysis.

micro total analysis systems (μ-TAS),1 or labs-on-a-chip,2 have become of major interest, especially to analytical chemists due to its desirable characteristics, such as reduction in reagent consumption, required space, and analysis time. Taking these advantages, we have demonstrated many applications, including flow-injection analysis,3,4 solvent extraction,5–7 immunoassay,8,9 organic synthesi...

This communication describes a mild construction of hybrid hydrogels with supramolecular-polymeric networks via a dual enzymatic reaction.

A unique and programmable peptide self-assembling system has been fabricated by using poly(ethylene glycol)-attached amphiphilic oligopeptide, which shows rapid self-assembly into well-organized beta-sheet nanofibers in response to an enzymatic reaction.