نتایج جستجو برای: fractalkine
تعداد نتایج: 925 فیلتر نتایج به سال:
The endothelium plays a central role in maintaining cardiovascular integrity, function, and the response to injury. A multitude of bioactive molecules is known to be expressed in and secreted from the endothelium under both physiological and pathophysiological circumstances. Xuan et al. uncover a unique role for fractalkine (FKN), a novel membrane-bound chemokine that is mainly expressed in end...
Epithelial ovarian carcinoma (EOC) is a deadly disease, and little is known about the mechanisms underlying its metastatic progression. Using human specimens and established cell lines, we determined that the G-protein– coupled seven-transmembrane fractalkine receptor (CX3CR1) is expressed in primary and metastatic ovarian carcinoma cells. Ovarian carcinoma cells robustly migrated toward CX3CL1...
Cells undergoing apoptosis are efficiently located and engulfed by phagocytes. The mechanisms by which macrophages, the professional scavenging phagocytes of apoptotic cells, are attracted to sites of apoptosis are poorly defined. Here we show that CX3CL1/fractalkine, a chemokine and intercellular adhesion molecule, is released rapidly from apoptotic lymphocytes, via caspaseand Bcl-2-regulated ...
Purpose: In this study, the relationship between postoperative cognitive functions and serum fractalkine, Glial Fibrillar Acidic Protein (GFAP) Cluster of differentiation 163 (CD163) levels in diabetic non-diabetic patients after open heart surgery was evaluated. Methods Materials: This research planned prospectively as observational clinical study. Cognitive functions, GFAP CD163 were evaluate...
M icroglia, highly mobile immune cells that reside in the central nervous system, are traditionally viewed as “barometers” of the brain because they rapidly respond to cellular damage caused by injury and disease by engulfing and cleaning up debris ( 1). Imaging studies, however, have revealed that microglia are also ceaselessly active in healthy brains, and other studies have shown that this a...
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