Aim: Data mining is the discovery process of beneficial information, not revealed from large-scale data beforehand. One fields in which widely used health. With mining, diagnosis and treatment disease risk factors affecting can be determined quickly. Association rules are one techniques. The aim this study to determine patient profiles by obtaining strong association with apriori algorithm, rul...

Betatrophin, also known as TD26/RIFL/lipasin/ANGPTL8/C19orf80, is a novel protein predominantly expressed in human liver. To date, several betatrophin orthologs have been identified in mammals. Increasing evidence has revealed an association between betatrophin expression and serum lipid profiles, particularly in patients with obesity or diabetes. Stimulators of betatrophin, such as insulin, th...

[This corrects the article on p. 441 in vol. 18, PMID: 25352765.].

Laser-scanning cytometry is presented as a tool allowing population scale analysis of ex vivo human brown adipogenic differentiation. It combines texture analysis and detection of Ucp1 protein content in single brown adipocytes of mixed cell populations with gene expression pattern and functional characteristics of browning. Using this method we could validate mouse data in human samples demons...

Department of Clinical Biochemistry, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, IR Iran Department of Physical Education and Sports Sciences, Tarbiat Modares University, Tehran, IR Iran Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, IR Iran Corresponding author: Mohammad Taghi Goodarzi, Hamadan University of Medical Sciences, ...

In a recent issue of JBMR, Colaianni and colleagues reported the relationship circulating irisin levels, myokine synthesized from skeletal muscle, with bone muscle parameters in sample older adults.(1) They showed that FNDC5 expression, an precursor, biopsies positively correlated osteocalcin mRNA biopsies, suggesting connection between these tissues. Interestingly, treatment decreased p21 sene...