Four outbreaks of foot-and-mouth disease (FMD) occurred from March to May 2000 in Miyazaki and Hokkaido Prefectures, Japan. FMD virus isolation was achieved by sampling probang materials from Japanese Black cattle in the third case found in Miyazaki Prefecture. The probang materials were inoculated to bovine kidney (BK) and bovine thyroid cell cultures. CPE was observed in the BK at two days po...

Foot-and-mouth disease (FMD) is a trans-boundary viral disease of livestock, which causes huge economic losses and constitutes a serious infectious threat for livestock farming worldwide. Early diagnosis of FMD helps to diminish its impact by adequate outbreak management. In this study, we describe the development of a real-time reverse transcription recombinase polymerase amplification (RT-RPA...

Foot-and-mouth disease (FMD) is a highly infectious affecting cloven-hoofed animals and causes significant economic losses to the livestock industry. The Type O PanAsia-2 (O PA-2) vaccine strain protective against wide range of serotype FMD virus (FMDV) strains in East Asia, A22 Iraq/24/64 (A22 IRQ) most widely used antigen banks. aim this study was produce antigens from PA-2 IRQ viruses using ...

Foot-and-mouth disease (FMD) is one of the most economically and socially devastating diseases affecting animal agriculture throughout the world. Although mortality is usually low in adult animals, millions of animals have been killed in efforts to rapidly control and eradicate FMD. The causing virus, FMD virus (FMDV), is a highly variable RNA virus occurring in seven serotypes (A, O, C, Asia 1...

Foot-and-mouth disease virus (FMDV) causes a highly contagious infection in cloven-hoofed animals. The format of FMD virus-like particles (VLP) as a non-replicating particulate vaccine candidate is a promising alternative to conventional inactivated FMDV vaccines. In this study, we explored a prokaryotic system to express and assemble the FMD VLP and validated the potential of VLP as an FMDV va...

BACKGROUND Aim of this study was to elucidate the relation between localised inflammatory heart disease and endothelial dysfunction in the peripheral circulation, considering circulating cytokines as a potential link. METHODS In 38 patients with non-ischemic heart disease, myocardial biopsies were examined for myocardial inflammation (immunohistology) and virus persistence (PCR). Cytokines (s...

290 The Veterinary Record, December 22/29, 2007 1971). Transfer of virus is more likely to occur in situations of high humidity. Virus can be recovered from nasal swabs of the people exposed to affected pigs 24 hours previously. FMD virus excretion in breath occurs before the appearance of lesions in affected species and can peak in bovine breath before lesions appear. Veterinary staff closely ...

After infection of the upper respiratory tract with foot-and-mouth disease (FMD) virus in immunized cattle, a drop in specific serum-neutralizing antibody activity was observed. Vaccinated cattle with high preexposure serum antibody titers had a precipitous drop for the first 4 days after virus exposure, followed by a rise in titer. This drop was also seen in passively immunized cattle with hig...