نتایج جستجو برای: fluphenazine

تعداد نتایج: 264  

2018
Morgan H James Ellen M McGlinchey Asrita Vattikonda Stephen V Mahler Gary Aston-Jones

Background Drug cues recruit prelimbic cortex neurons that project to ipsilateral nucleus accumbens core. However, it is not known if the same is true for prelimbic cortex projections that decussate to innervate contralateral nucleus accumbens core. Further, a role for prelimbic cortex dopamine signaling in cued reinstatement of cocaine seeking has not been shown. Methods We assessed Fos expr...

Journal: :Evidence-based mental health 2015
Enrico G Castillo T Scott Stroup

INTRODUCTION The personal and societal costs of schizophrenia spectrum disorders are immense. Affected individuals may experience positive, negative and mood symptoms; medical and substance use comorbidities; and cognitive impairment that significantly impair social and occupational functioning. Globally, schizophrenia is a leading cause of years lost to disability, with a particularly large bu...

Journal: :The European journal of neuroscience 1992
Abram Akopian John McReynolds Reto Weiler

The effect of phorbol esters on the light-evoked responses of horizontal cells were studied in the turtle eyecup preparation. Phorbol esters caused a reduction in receptive field size and a significant decrease in the amplitude of responses to annular and full-field illumination; however, they caused only minor changes in responses to small spots in the receptive field centre. The dark membrane...

Journal: :CNS spectrums 2017
Jonathan M Meyer

There has been increasing recognition that antipsychotic nonadherence is common across all stages of schizophrenia, starting from the first episode. Moreover, numerous meta-analyses of the existing literature indicate superiority of long-acting injectable (LAI) over oral antipsychotics when one adjusts for the greater illness severity and duration among patients in LAI antipsychotic trials. The...

Journal: :Evidence-based mental health 2002
Gary Remington Shitij Kapur

Main results 18 studies (2214 patients) met the selection criteria. Study duration ranged from 3 weeks to 1 year (mean 12 wks). Patients were mostly men in their 30s with moderate to severe schizophrenia (mean duration 3–37 y). Comparators were usually haloperidol and placebo; 4 studies compared amisulpride with flupentixol, perazine, and fluphenazine. Amisulpride led to a greater mean reductio...

Journal: :The American journal of physiology 1999
Alexander A Mongin Zhaohui Cai Harold K Kimelberg

Cell swelling results in regulatory activation of multiple conductive anion pathways permeable toward a broad spectrum of intracellular organic osmolytes. Here, we explore the involvement of extracellular and intracellular Ca2+ in volume-dependent [3H]taurine efflux from primary cultured astrocytes and compare the Ca2+ sensitivity of this efflux in slow (high K+ medium induced) and fast (hyposm...

Journal: :Chromatographia 2022

Abstract Nowadays, when analysts develop a new method, they are taking into consideration the green aspects of developed method. Two chromatographic methods were for determination antidepressant pharmaceutical combination nortriptyline hydrochloride and fluphenazine in presence their potential impurities assessed using four tools; eco-scale, analytical greenness profile (AGP), metric approach (...

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