We investigated the transmission characteristics of formalin fixed human liver samples in which normal tissue and malignant tumor were mixed using terahertz (THz) coherent synchrotron radiation at an infrared free-electron laser (FEL) facility Nihon University. Infrared-FEL imaging has indicated that amount water molecules is not different from tissue. However, incipient was lower than THz beca...

Scaffolding plays a pivotal role in tissue engineering. To mimic the architecture of a natural extracellular matrix component-collagen, nona-fibrous matrices have been created with synthetic biodegradable polymers in our laboratory using a phase-separation technique. To improve the cell seeding, distribution, mass transport, and new tissue organization, three-dimensional macroporous architectur...

We studied at necropsy atherosclerotic plaque composition in the four major (right, left main, left anterior descending, and left circumflex) epicardial coronary arteries in 15 patients who died of consequences of an acute myocardial infarction (AMI) and in 12 patients with sudden coronary death (SCD) without AMI. The coronary epicardial arteries were sectioned at 5-mm intervals, and a Movat-st...

Perinephritic abscess may be a sequel to a localization of organisms in the kidney parenchyma, with extensioni either by way (a) of the lymphatics whlichi pass through the fibrous capsule from the cortex of the kidney to the perinephritic fat or (b) by contiguity of infected tissues. For this reason a guarded prognosis should he given in all cascs of perillephritic abscess, and the possibility ...

Solitary fibrous tumors are rare tumors originating from the mesenchymal tissue. In most cases they arise from the subpleural tissue but have also been described in other locations in the body. Most such tumors in the head and neck region occur in the orbit. Although malignant tumors can occur, benign tumors are far more common. The therapy is surgical excision. For a conclusive diagnosis, a ty...

Stromal invasion (invasive growth of tumor tissue into portal tracts and fibrous septa) is now recognized as the most important finding in the diagnosis of the well-differentiated type of early hepatocellular carcinomas (HCCs). In differentiating stromal invasion from pseudoinvasion (benign hepatic tissue in fibrous stroma), the following 5 items are useful: (1) macroscopic or panoramic views o...

Due to osteoconductivity of hydroxyapatite (HA), HA/polymer composite scaffolds have been investigated for bone tissue engineering by various groups. In scaffold fabrication, electrospinning of ultrafine fibrous scaffolds incorporated with substantial amounts of evenly distributed HA nanoparticles is still a challenge. The problem of nanoparticle agglomeration not only reduces the electrospinni...

The giant cell fibroma is a localized reactive proliferation of fibrous tissue, much like the irritation fibroma. It usually small, may have be sessile/peduncalated. It is painless, often has lobules/ nodules on its surface. It contains cells with large, stellate shaped fibroblasts, near the surface of the fibrous mass, beneath the overlying epithelium. A female patient aged 45 years presented ...

The foreign body response (FBR) is described as the host's response to implanted biomaterials, which involves a complex cascade of immune modulators. The dynamic changes of immune cells, inflammatory cytokines and the formation of a fibrous capsule remain to be elucidated. In the present study, a model of subcutaneous implantation of a tissue expander was used. The results revealed that macroph...

Bone tissue reactions to EBA, IRM, and cyanoacrylate cement (Base Liner) were studied in the rat mandible using an intraosseous implant method. Osseous cavities (1.4 mm in diameter) were surgically created in the mandibles, and materials were implanted in 60 male Wistar rats. Each specimen was evaluated histologically after 4 and 8 weeks. The development of fibrous connective tissue in direct a...