BACKGROUND AND OBJECTIVES To investigate out-of-hospital treatment, including fibrinolysis, in patients with ST-elevation acute myocardial infarction and to determine the 1-year survival rate. METHODS Prospective cohort study based on an ongoing out-of-hospital registry of patients with ST-elevation acute myocardial infarction who were treated by out-of-hospital emergency teams in Andalusia, ...

Serial changes in coagulation and fibrinolysis studied among 42 patients admitted to hospital with a wide variety of injuries are reported. The first hours after trauma are dominated by an acceleration of fibrinolysis (clot lysis) and clotting time which are often followed by an abrupt rebound to prolonged fibrinolysis and normal clotting. Evidence is presented that acceleration of fibrinolysis...