نتایج جستجو برای: fertility regulation

تعداد نتایج: 598402  

2017
Abinaya Nathan Peter Reinhardt Dagmar Kruspe Tjard Jörß Marco Groth Hendrik Nolte Andreas Habenicht Jörg Herrmann Verena Holschbach Bettina Toth Marcus Krüger Zhao-Qi Wang Matthias Platzer Christoph Englert

Although the zinc finger transcription factor Wt1 has been linked to female fertility, its precise role in this process has not yet been understood. We have sequenced the WT1 exons in a panel of patients with idiopathic infertility and have identified a missense mutation in WT1 in one patient out of eight. This mutation leads to an amino acid change within the zinc finger domain and results in ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Hey-Joo Kang Zhaohui Feng Yvonne Sun Gurinder Atwal Maureen E Murphy Timothy R Rebbeck Zev Rosenwaks Arnold J Levine Wenwei Hu

The tumor suppressor protein p53 plays an important role in maternal reproduction in mice through transcriptional regulation of leukemia inhibitory factor (LIF), a cytokine crucial for blastocyst implantation. To determine whether these observations could be extended to humans, a list of single-nucleotide polymorphisms (SNPs) in the p53 pathway that can modify the function of p53 was assembled ...

Journal: :Cold Spring Harbor perspectives in biology 2009
Wenwei Hu

The p53 family of genes (p53, p63, and p73) is conserved over evolutionary time scales. Although the functions of p53 gene and its protein as a tumor suppressor have been firmly established, the earliest functions for the p53 ancestral genes in worms and flies are to ensure germ-line genomic integrity and the fidelity of the developmental process. In vertebrates, the p53 family of genes retains...

Journal: :Frontiers in bioscience 2013
Marija Curlin Danijel Bursac

Structure of human cervical mucus plays a pivotal role in female fertility and protection of reproductive health. Investigation of biochemical and biophysical structure of cervical mucus remains a challenge due to complex structural proteins, high content of oligosaccharides and cyclic variability of its structure. We present the current knowledge on chemical and biophysical features of cervica...

Journal: :حیات 0
z rahnavard m saadaat hashemi h khalkhaali f va’ez-zadeh

total fertility rate relates to the number of children that a woman bears in the fertility period of her life. fertility function is one of the most important health and population indicators. this indicator affects social, health, economic and cultural factors. this study is an ecological or correlative one. factors affecting total fertility rate in iran in the year 2000 are studied in this pa...

2014
Aurelija Blaževičienė Irayda Jakušovaitė Alina Vaškelytė

BACKGROUND This article analyzes several key issues in the debate: the acceptability of in vitro fertilization; regulation of assisted reproduction and the possibilities of reimbursement for assisted reproduction treatment in Lithuania. METHOD Two groups of respondents participated in the survey: fertile women and women with fertility disorders. 93 completed questionnaires from women with fer...

Journal: :Cell 2006
S Chu J Gunther

Recent work provides new insights into the regulation of fertility in animals, plants, and unicellular eukaryotes. These findings suggest that fertility is controlled by the dynamic and complex interplay of numerous factors including the regulation of RNA stability, protein translation, chromatin structure, and chromosomal organization. In a recent study, Chu et al. (2006) sought factors that a...

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