Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and discussed current general management approaches. New technical modalities and patients' own desire for motherhood should be integral and paramount in...

Freezing of eggs or ovarian tissue to preserve fertility for cancer patients has been studied since 1994 with Gosden’s original paper in sheep, and before that in smaller mammals for decades prior. Clinically, this tactic has enjoyed great success. Despite the rising popularity of vitrification for egg freezing, it is often done incorrectly, forgetting the original principles Kuwayama establish...

For cancers of reproductive system in women, fertility preservation is complex. Fertility is also affected by therapies, however prevention is possible. Radiotherapy affects gonads, uterus, and subsequent pregnancy outcomes in all ages. However, degree and damage depend on dose, irradiation field, and age at the time of exposure. Ovarian transposition is considered if ovarian involvement is unl...

OBJECTIVE To measure the parental attitudes toward fertility preservation in boys with cancer. DESIGN Retrospective cohort study. SETTING Questionnaire survey via regular mail. PATIENT(S) A total of 465 families whose sons were already treated for cancer. INTERVENTION(S) The questionnaire was designed for two groups based on child's age at the time of cancer diagnosis: <12 and ≥12 years...

INTRODUCTION Patients faced with infertility due to spermatogonial stem cell loss have currently semen cryobanking as only option for fertility preservation. A growing group of patients cannot benefit from this strategy as they are devoid of spermatozoa or even of any spermatogenic cell at the time of diagnosis. We therefore aimed at investigating alternative strategies to preserve or restore f...

BACKGROUND Many children treated for cancer are at risk of infertility, but for girls and prepubertal boys, all fertility preservation techniques remain experimental. We have assessed UK practice relating to information provision about the effects of cancer treatment on fertility and options for fertility preservation. METHODS Paediatric oncologists prospectively completed a data form for eac...

With 21,650 new cases every year, ovarian cancer is currently the fifth leading cause of death from all cancers in women in the USA [1]. Among gynecological cancers, it is the leading cause of death, typically presenting with stage III/IV disease. At present, 12.2% of ovarian cancers occur in women younger than 40 years of age [2]. Most of these cases are tumors of low malignant potential, mali...

Fertility preservation is an important but often neglected need of cancer patients. There are several options available but many are considered experimental or are unproven. Most require interventions that can postpone the initiation of cancer treatment. The options include surgical procedures to move the ovaries out of the path of a radiation field, prophylactic medical therapy with gonadotrop...

Increasing numbers of young transgender people are now using medical technologies to achieve a physical gender transition. However, the procedures of physical gender transition might cause temporary or permanent sterility. Thus many transgender people are now using fertility preservation technologies. Nonetheless, they can experience dilemmas in making reproductive and family-building decisions...

In the United Kingdom each year 11 000 patients aged 15-40 years are diagnosed with cancer, and more than half of themwill live formore than five years. 2 Patients want quality of life, including the ability to have a family, and many request advice on fertility preservation. This review describes the fertility preservation techniques available and recent recommendations from the UK and the Uni...