Hemoglobin (Hb) is a toxic molecule responsible for the extreme lethality associated with experimental Escherichia coli peritonitis, but the mechanism has yet to be elucidated. Hb, but not globin, showed toxic effects in a live E. coli model but not in a model using killed E. coli. Methemoglobin, hematin, and the well-known Fenton reagents iron and iron-EDTA demonstrated the same lethal effect ...

Optimization of the simultaneous chemical and biological mineralization of perchloroethylene (PCE) by modified Fenton's reagent and Xanthobacter flavus was investigated by using a central composite rotatable experimental design. Concentrations of PCE, hydrogen peroxide, and ferrous iron and the microbial cell number were set as variables. Percent mineralization of PCE to CO2 was investigated as...

The structure of macromolecules and their complexes dictate their biological function. In "footprinting", the solvent accessibility of the residues that constitute proteins, DNA and RNA can be determined from their reactivity to an exogenous reagent such as the hydroxyl radical (·OH). While ·OH generation for protein footprinting is achieved by radiolysis, photolysis and electrochemistry, we pr...

Various aspects of the participation of Fenton chemistry in biology and medicine are reviewed. Accumulated evidence shows that both hydroxyl radical and ferryl [Fe(IV)=O]2+ can be formed under a variety of Fenton and Fenton-like reactions. Some examples of metal-independent hydroxyl radical production are included. Extracellular Fenton reaction is illustrated by the white rot and brown rot wood...

Oxidative stress has been implicated both in senile and diabetic cataractogenesis and recent evidence suggest that the lipid peroxidation product, 4-hydroxynonenal (HNE) mediates the oxidation-induced toxicity. Using human lens epithelial cells (HLEC) and rat lens we have demonstrated that HNE and oxidants such as Fenton reagent induce opacification in the rat lens and apoptosis in HLEC and len...

A novel, rapid and simple method is described for the synthesis of magnetic MIL-100(Fe) with novel Fe3O4 morphology, which significantly improved the sustainability of conventional fabrication processes in several aspects. The magnetic MOFs were prepared (i) in one pot (instead of multiple steps), (ii) at room temperature (instead of temperatures over 150 °C), (iii) within a few hours with exce...

The hydroxyl radical (OH radical) formation rates from the photo-Fenton reaction in river and rain water samples were determined by using deferoxamine mesylate (DFOM), which makes a stable and strong complex with Fe(III), resulting in a suppression of the photo-Fenton reaction. The difference between the OH radical formation rates with and without added DFOM denotes the rate from the photo-Fent...

Abstract Alum sludge (AS) is produced in inevitable amounts from drinking water treatment plants. Also, dye-contaminating wastewater usually discharged textile industries that must be treated to meet the environmental authorities; thus, Fenton’s reagent a suitable candidate. However, reducing quantity of chemicals used Fenton reactions can partly achieved by an industrial ecology approach. This...

The effect of Fenton's reagent (FR) on surface and dispersion properties of black liquor (BL) was investigated. These properties were compared to those of indulin C (IC), a commercial lignin, and egg lecithin (Le). FR was applied at two different bulk concentrations of H2O2 (160 and 320 mM). At pH 8, a minimum in surface tension for the Fenton treated BL was observed. The dispersant ability of ...