Imaging the structure of molecules in transient-excited states remains a challenge due to the extreme requirements for spatial and temporal resolution. Ultrafast electron diffraction from aligned molecules provides atomic resolution and allows for the retrieval of structural information without the need to rely on theoretical models. Here we use ultrafast electron diffraction from aligned molec...

For semimetals such as bismuth, ultrafast femtosecond laser-excited coherent phonons at laser fluences below the damage threshold have been studied extensively. In this work, we investigate whether or not coherent phonon oscillations contribute to material's permanent damage, or can enhance or suppress such damage. We employed temporally-shaped femtosecond pulses to either enhance or cancel coh...

We study the effects of the interaction of 40-fs Ti-sapphire laser radiation at 800 nm with biological materials—proteins or intact Bacillus spore, dissolved or suspended in pure water, respectively. The estimated laser intensity at the target is 1013 W∕cm2. On the molecular level, oxidation of solvent-accessible parts of proteins has been observed even after a single femtosecond laser pulse, a...

We present a technique to measure the refractive index profile of direct laser written waveguides. This method has the potential for straightforward implementation in an existing laser fabrication system. Quantitative phase microscopy, based on the Transfer of Intensity equation, is used to analyse waveguides fabricated with an ultrashort pulsed laser embedded several hundred micron below the s...

Creation of consistently sized, centrally located, circular capsulotomies has long been the goal of the cataract surgeon. It has been believed that such capsular openings minimize changes in effective lens position after cataract surgery. Manual techniques, even in the best hands and utilizing mechanical or optical devices, are unable to guarantee this. The advent of the femtosecond laser, for ...

Purpose. To report the incidence and outcomes of anterior chamber gas bubble formation during femtosecond laser flap creation for laser-assisted in situ keratomileusis (LASIK). Methods. The charts of 2,886 consecutive eyes that underwent femtosecond LASIK from May 2011 through August 2014 were retrospectively reviewed. The incidence, preoperative characteristics, intraoperative details, and pos...

INTRODUCTION Laser vision correction for hyperopia is challenging. The purpose of the study was to assess the refractive outcomes of femtosecond-assisted laser in situ keratomileusis (LASIK) for hyperopic correction using wavefront-optimized ablation profiles. METHODS This retrospective case series study included 20 Egyptian patients (40 eyes) with hyperopia or hyperopic astigmatism with a me...

PURPOSE To report the anterior segment imaging characteristics after femtosecond laser assisted cataract surgery. METHODS Cataract surgery was performed with the LenSx femtosecond laser (Alcon-LenSx Inc., Aliso Viejo, CA) in 40 eyes of 40 patients. The laser was programmed to perform a 4.5-mm capsulorhexis, a cross-pattern fragmentation of the nucleus, a 2.8-mm main incision, and a 1.0-mm sid...

BACKGROUND The purpose of this work is to report our experience using the new Z8 laser system for femtosecond laser-assisted cataract surgery (FLACS) and to provide a sample of the performance and safety results using this new technology. METHODS This prospective observational study was performed at the Swiss Eye Research Foundation, Eye Clinic ORASIS, Reinach, Switzerland. Fourteen patients ...

s 2012 begins, femtosecond lasers have been used for more than a decade to create LASIK fl aps. 1 Starting with a single model, these lasers have gone through multiple iterations, and now multiple competing technologies are available in the market place worldwide. In the United States, recent surveys demonstrate continued increasing market share. Now more than half of all LASIK procedures are p...