Various assisted reproductive techniques have been developed and refined to obtain a large number of offspring from genetically superior animals or obtain offspring from infertile (or subfertile) animals. The embryo transfer is one assisted reproductive technique developed well, aimed at increased productivity of selected females, disease control, importation and exportation of livestock, rapid...

Sex-lethal (Sxl) is the master switch gene for somatic sex determination in Drosophila melanogaster. In XX animals, Sxl becomes activated and imposes female development; in X(Y) animals, Sxl remains inactive and male development ensues. A switch gene for sex determination, called F, has also been identified in the housefly, Musca domestica. An active F dictates female development, while male de...

Cyclin D1 is a known oncogene and a key regulator of cell cycle progression. Amplification of the cyclin D1 gene and its overexpression have been associated with aggressive forms of human hepatocellular carcinoma (HCC). In this study, two independent lines of transgenic mice have been generated that express cyclin D1 under the control of the rat liver fatty acid binding protein promoter. This t...

The patterns of adult copulatory behaviour can be observed in piglets. This sex play is more frequent in young boars than in young sows and reaches a peak during the second neonatal month. The castration of young boars within 5 min after birth (7 animals) eliminated the intense sex play of the second month. Gonadectomy at 30 days (3 animals) did not change mounting frequency during the second m...

To understand the mechanism of Multiple Sclerosis (MS), an autoimmune demyelinating disease, the researchers developed an experimental animal model for MS, which is called EAE (Experimental Allergic Encephalomyelitis). There are several methods for inducing this animal model. In this research the active EAE, which is developed by injecting bovine myelin antigens into genetically susceptibl...

introduction: depression is one of the most frequent psychiatric disorders in the world with occurs with higher incidence in women. in the present study, the effect of water-alcoholic extract of papaver rhoeas l. on forced swimming test (fst) in swiss-webster mice were examined. methods: we used swiss-webster mice (20-25 g) to execute fst on them. the plant extract (1, 10, 30, and 100 mg/kg) wa...

Various assisted reproductive techniques have been developed and refined to obtain a large number of offspring from genetically superior animals or obtain offspring from infertile (or subfertile) animals. The embryo transfer is one assisted reproductive technique developed well, aimed at increased productivity of selected females, disease control, importation and exportation of livestock, rapid...

BACKGROUND Trimethylolpropane triacrylate (TMPTA) is used as an ingredient in a wide variety of coatings, resins, photosensitive materials, and superabsorbent baby diapers. We studied the effects of TMPTA on male and female rats and mice to identify potential toxic or cancer-related hazards. METHODS We applied solutions containing TMPTA in acetone on the backs of male and female rats and mice...

Assessment of acute toxicity is a necessary stage preclinical research the substance GIZh-298. The aim present study Methods. GIZh-298 was administered once intraperitoneally to mice at doses 200-330 mg/kg. Equivalent volume 1 % starch solution animals control groups. Periods intoxication and death with detailed description observed clinical picture were registered. Euthanasia pathoanatomical d...