BACKGROUND AND ETIOLOGICAL AGENTS Upper respiratory tract disease (URTD) and it is the most common disease reported among the approximately 2 million to 6 million cats housed in US shelters annually and is often a cause of euthanasia because of the risks of transmission of infection throughout the shelter population and the negative effects on adoptability of infected cats. The combination of s...

OBJECTIVES (1) To describe the ultrastructural features of corneal sequestra in cats; and (2) to enhance our understanding regarding the pathogenesis of feline corneal sequestration. METHODS Nine corneal sequestra were harvested via keratectomy from globes of nine cats. The sequestra were routinely fixed then postfixed for high resolution light and transmission electron microscopy (HR-LM and ...

Background: Feline calicivirus (FCV) and felid herpesvirus type 1 (FeHV-1) are widely distributed in the feline population. These viruses are the main cause of upper respiratory tract disease in this species, and FCV can also causes oral disease characterized by stomatitis and ulcers. Furthermore, FCV has been associated with a systemic hemorrhagic syndrome named FCV-associated virulent systemi...

We analyzed antibody responses in sera from feline immunodeficiency virus (FIV)-infected and uninfected cats. A strong antiviral response to the viral surface glycoprotein (SU) was noted in both natural and experimental infections. In addition, 143 of 226 FIV-infected animals (63%) also expressed antibodies to the primary binding receptor, CD134, whereas cats infected with other feline RNA viru...

We offer eight well-characterized anti-SAA MAbs for the detection of feline, canine and equine SAA. These MAbs were selected from a pool of over forty MAbs that were raised against human SAA (SAA19, SAA21, SAA11), canine SAA (VSA34, VSA31, VSA38), or synthetic peptides derived from the region 79-104 a.a.r. of canine SAA (VSA2, VSA43). Isotypes and specificities of the antibodies are shown in Ta...

Forty humane society cats with suspected bacterial upper respiratory infections (URIs) were studied in order to compare amoxycillin and pradofloxacin for treatment of rhinitis and describe common pathogens. Nasal discharges were collected prior to random placement into one of three treatment groups. Cats failing to initially respond were crossed to the alternate drug. Drug toxicity was not note...