White wine fermentations are typically performed in an entirely batchwise manner, with yeast nutrients only added at the beginning of fermentation. This leads to slow (2+ weeks) fermentation cycle times, large capital expenditures required increase winery processing capacity. Prior attempts speed via increasing temperature have resulted unpalatable wine, and continuous is uneconomical impractic...

Bacillus subtilis 3NA reaches high cell densities during fed-batch fermentation and is an interesting target for further optimization as a production strain. Here, we announce the full genome of B. subtilis 3NA. The presence of specific Bacillus subtilis 168 and W23 genetic features suggests that 3NA is a hybrid of these strains.

Animal waste fats were explored as a fermentation substrate for the production of high-value unsaturated single cell oil (SCO) using oleaginous fungi, Mucor circinelloides and Mortierella alpina. Both strains showed good growth lipid accumulation when animal fat carbon source. The biomass concentration 16.7 ± 2.2 gDCW/L content 54.1%wt (of dry weight) obtained in shake flask experiments, surpas...

An optimal control solution to a fed-batch fermentation process, responding to a competition call, was developed using the NEOS (network enabled optimization solution) server (http://www-neos.mcs.anl.gov/neos/). Substantial improvement to the nominal performance achieved in the paper demonstrates the ability of the NEOS server and the asynchronous parallel pattern search algorithm.

We used the software Optferm to model and optimize the bioprocess of escherichia coli fermentation, simulating the conditions of a fed-batch bioreactor. The results, obtained by employing different AI approaches, provided useful orientation for nutrient feed strategies for increased productivity. In conclusion, we believe in silico tools can perform a rapid and valid optimization of bioprocesse...

In this paper we review recent advances on the practice and theory of process control with particular emphasis to the operation of bioreactors. We present in detail a case-study on the modelling, model-based identification and adaptive control of fed-batch baker's yeast fermentation. 1. Practice and Theory of Process Control An Overview 1.

Bioencapsulation of microbial cells in silica-based matrices has proved to be a good strategy to enhance the biosynthetic capabilities and viability of bioproducers. In the present study, mycelium and pellet cultures of strain Aspergillus oryzae PP were successfully immobilized in sol-gel hybrid matrices composed of tetraethylorthosilicate as an inorganic precursor, 5% (w/v) starch and 10 or 15...