YeastCandida bombicola is known to produce sophorolipids from a variety of saccharic and lipidic feed-stocks. In the current study, the influence f fatty acid carbon chain length, unsaturation, source of low-cost industrial lipid feed-stocks, and nickel content in lipid feed-stocks on sophorolipid roduction by C. bombicola were investigated. Saturated and monounsaturated C18 fatty acid gave the...

With the remarkable increase of genomic sequence data of microorganisms, novel tools are needed for comprehensive analyses of the big sequence data available. The self-organizing map (SOM) is an effective tool for clustering and visualizing high-dimensional data, such as oligonucleotide composition on one map. By modifying the conventional SOM, we developed batch-learning SOM (BLSOM), which all...

Antibacterial nanocomposite polyester (PET) fibres were melt spun by adding nano ZnO loaded Linear Low Density Polyethylene (LLDPE) master batch (MB) to the PET chips. The influence of content of nano ZnO on the antibacterial properties, crystallization behaviour and mechanical properties was studied. It was found that PET composite fibres having 1 % nano ZnO showed the optimum antibacterial ac...

Batch-to-batch iterative learning control of a fed-batch fermentation process using batchwise linearised models identified from process operation data is presented in this paper. Due to model-plant mismatches and the present of unknown disturbances, off-line calculated control policy may not be optimal when implemented to the real process. The repetitive nature of batch process allows informati...

Considers the problem of reconstructing a continuous-tone (contone) image from its halftoned version, where the halftoning process is done by error diffusion. The authors present an iterative nonlinear decoding algorithm for halftone-to-contone conversion and show simulation results that compare the performance of the algorithm to that of conventional linear low-pass filtering. They find that t...

CHO cell culture high productivity relies on optimized culture medium management under fed-batch or perfused chemostat strategies enabling high cell densities. In this work, a dynamic metabolic model for CHO cells was further developed, calibrated and challenged using datasets obtained under four different culture conditions, including two batch and two fed-batch cultures comparing two differen...

Background Glutamine metabolism represents one of the major targets in metabolic engineering and process optimization due to its importance as cellular energy, carbon and nitrogen source. Metabolic flux analysis represents a powerful method to investigate the physiology and metabolism of cells [1]. Classical metabolic flux analysis methods require steady state conditions. However, industrially ...

This report describes the building of a simulator for prediction of the dissolved oxygen concentration, the oxygen transfer rate and the concentration of carbon dioxide in a fermentation process. The steady state models were made using the linguistic equations method. The dynamic models were made using Simulink ® toolbox in the Matlab ® . At the beginning, some basics about fermentation and mic...

We address the problem of finding an optimal feedback control for feeding a fed-batch bioreactor with one species and one substrate, from a given initial condition to a given target value in a minimal amount of time. Mortality rate for the biomass and nutrient recycling are taken into account in this work. The optimal synthesis (optimal feeding strategy) has been obtained by Moreno in 1999 when...