While intestinal transport systems for metabolites such as carbohydrates have been well characterized, the molecular mechanisms of fatty acid (FA) transport across the apical plasmalemma of enterocytes have remained largely unclear. Here, we show that FATP4, a member of a large family of FA transport proteins (FATPs), is expressed at high levels on the apical side of mature enterocytes in the s...

Two experiments were conducted to determine the effect of source of fatty acids (FA) fed as tallow or calcium salts of fish and palm oils (CaSFO) on performance of dairy cows. In experiment 1, 738 multiparous Holstein cows were fed a diet with either 18 g/kg of tallow or 19 g/kg of CaSFO to supply equal amounts of FA in two replicates per treatment. In experiment 2, 331 multiparous cows were fe...

Milk samples were collected in early lactation (8–14 days milk; DIM) and late (199–326 from 11 cows to assess the differences bovine milk fatty acid (FA) triacylglycerol (TAG) composition, FA positional distribution TAG structure, solid fat content (SFC). Cows that negative energy balance, mobilised C16:0, C18:0, C18:1cis9 their body stores, increasing concentrations of these fat. These high C1...

The effects of diets (i.e., high fibre, HF and high concentrate, HC) supplemented with either fumaric acid (FUM; 8 mmol/L) or maleic acid (MAL; 8 mmol/L) and different plant oils (35.0 g/kg dry matter; sunflower, SO; rapeseed, RO; and linseed, LO) on rumen sheep fatty acids (FA) concentration and biohydrogenation (BH) in batch cultures were examined. The oils rich in linoleic acid (SO, 535 g/kg...

Diabetic nephropathy is the leading cause of end-stage renal disease and is associated with an increased risk of cardiovascular events. Dietary omega-3 fatty acid (FA) has cardioprotective effect and is associated with a slower deterioration of albumin excretion in patients with diabetic nephropathy. In this study, we evaluated the effect of omega-3 FA on proteinuria in diabetic nephropathy pat...

Tetradecylthioacetic acid (TTA) is a non-beta-oxidizable fatty acid analog, which potently regulates lipid homeostasis. Here we evaluate the ability of TTA to prevent diet-induced and genetically determined adiposity and insulin resistance. In Wistar rats fed a high fat diet, TTA administration completely prevented diet-induced insulin resistance and adiposity. In genetically obese Zucker (fa/f...

AIM To investigate the fatty acid-based functional lipidomics of patients on long-term home parenteral nutrition receiving different intravenous lipid emulsions. METHODS A cross-sectional comparative study was carried out on 3 groups of adults on home parenteral nutrition (HPN), receiving an HPN admixture containing an olive-soybean oil-based intravenous lipid emulsion (IVLE) (OO-IVLE; n = 15...

Digestion of milkfat releases some long-chain (18-carbon) fatty acids (FAs) that can provide health benefits to the consumer, yet because they are found in small amounts and can be difficult to identify, there is limited information on the effects that common fluid milk processing may have on the digestibility of these FAs. This study provides FA profiles for raw and combinations of homogenized...

This study aims to assess near-infrared reflectance spectroscopy feasibility for predicting beef fatty acid (FA) composition. Experimental scheme included four breeds (Angus, Blond d'Aquitaine, Charolais, Limousin) and three muscles, Longissimus thoracis (LT), Rectus abdominis (RA), Semitendinosus (ST). The results showed that 1) increasing FA content variability with several breeds increased c...