OBJECTIVE To compare the use of GHb and fasting plasma glucose (FPG) to define the metabolic syndrome (MetS). RESEARCH DESIGN AND METHODS Data from the U.S. National Health and Nutrition Examination Survey 1999-2006 were used. MetS was defined using the consensus criteria in 2009. Raised blood glucose was defined as either FPG >or=100 mg/dl (5.6 mmol/l) or GHb >or=5.7%. RESULTS In 2003-2006...

We determined optimal fasting plasma glucose (FPG) cutoff values predictive of future diabetes development in a group of middle-aged Koreans who visited a health promotion center. The medical records of 2,964 subjects, who attended the Health Promotion Center in 1998 and 2003, were examined. Subjects were classified into four groups according to their baseline FPG values (Group 1:FPG <5.0 mM/L;...

compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial. In the print version of the article listed above, the fasting plasma glucose (FPG) data in conventional units (mg/dL) are not correct in Fig. 2C. The FPG data in SI units are correct; therefore, the conclusions do not change. The cor...

D e s c r i p t i o n o f t e s t s a n d d i a g n o s t i c s t a n d a r d FPG and 2-hour post–glucose-load (i.e., after ingestion of 75 g of oral glucose) plasma glucose were measured using enzymatic methods with a hexokinase reference. HbA1c was analyzed using high-performance liquid chromatography. The 1998 WHO diagnostic criteria were used as the “gold standard” to classify the participa...

BACKGROUND Achieving fasting plasma glucose (FPG) target may not reflect hemoglobin A1c (HbA1c) target achievement. OBJECTIVE Illustrate the blood glucose patterns contributing to HbA1c > 7% in patients whose FPG was < 130 mg/dl and correlation between HbA1c and plasma glucose at various times. The contribution of caloric intake, carbohydrate consumption and glycemic index of food to plasma g...

OBJECTIVE The purpose of this study was to estimate medical costs associated with elevated fasting plasma glucose (FPG) and to determine whether costs differed for patients who met the 2003 (> or = 100 mg/dl) versus the 1997 (> or = 110 mg/dl) American Diabetes Association (ADA) cut point for impaired fasting glucose. RESEARCH DESIGN AND METHODS We identified 28,335 patients with two or more ...

OBJECTIVE To re-evaluate the relationship between glycemia and diabetic retinopathy. RESEARCH DESIGN AND METHODS We conducted a data-pooling analysis of nine studies from five countries with 44,623 participants aged 20-79 years with gradable retinal photographs. The relationship between diabetes-specific retinopathy (defined as moderate or more severe retinopathy) and three glycemic measures ...

Patients with polycystic ovary syndrome (PCOS) present a higher risk for abnormalities of glucose metabolism (AGM). For to study this in our population, we submitted 85 patients, with body mass index (BMI) of 28.5 +/- 6.6 kg/m(2) and aged 25.5 +/- 5.4 years old, to an oral glucose tolerance test (OGTT), and assessed the impact of BMI on the prevalence of impaired glucose tolerance (IGT) and of ...

OBJECTIVE Postprandial hyperglycemia characterizes early type 2 diabetes. We investigated whether ameliorating postprandial hyperglycemia with acarbose would prevent or delay progression of diabetes, defined as progression to frank fasting hyperglycemia, in subjects with early diabetes (fasting plasma glucose [FPG] <140 mg/dl and 2-h plasma glucose > or =200 mg/dl). RESEARCH DESIGN AND METHOD...

Maternally inherited familial hypercholesterolemia (FH) impairs glucose metabolism and increases cardiovascular risks in the offspring to a greater degree than paternal inherited FH. However, it remains unknown whether hypertriglyceridemia affects glucose metabolism via inheritance. In this study, we sought to compare the impact of maternally and paternally inherited hypertriglyceridemia on glu...